Clinical and pharmacological group: & nbsp

Gastrointestinal drugs

Included in the formulation
  • Bifiform®
    capsules inwards 
  • АТХ:

    A.07.F.A   Antidiarrhoeal preparations of biological origin regulating the balance of intestinal microflora

    Pharmacodynamics:

    The drug is an eubiotic. Strains Enterococcus faecium and Bifidobacterium longum, which are part of the drug, are natural symbiotic bacteria that inhabit the gastrointestinal tract. The drug has a normalizing effect on the quantitative and qualitative composition of the intestinal microflora. The effect is caused both by the direct direct effect of the constituent components (high antagonistic activity against pathogenic and conditionally pathogenic microorganisms) and indirectly by stimulation of the local intestinal link of immunity (activation of immunoglobulin A synthesis, induction of endogenous interferon synthesis).

    Bifidobacterium longum has a high survival rate in the human intestine and a high growth rate. Inclusion in the preparation of apatogenic enterococcus Enterococcus faecium, colonizing the normal small intestine, can have a positive effect on the condition and digestive functions of not only the thick, but also the small intestine, especially in the presence of fermentation dyspepsia and the phenomena of flatulence.

    Pharmacokinetics:

    There is no data on the pharmacokinetics of the drug.

    Indications:

    - diarrhea caused by acute and exacerbation of chronic gastroenteritis, rotavirus infection;

    - antibiotic-associated diarrhea;

    - traveler's diarrhea;

    - in the complex therapy of acute intestinal infections;

    - in the complex therapy of chronic gastrointestinal diseases, such as colitis, irritable bowel syndrome and other gastrointestinal disorders of functional genesis;

    - normalization of intestinal microflora, treatment and prevention of dysbacteriosis and maintenance of the immune system in children older than 2 years and adults;

    lactose intolerance;

    - as part of complex standard eradication therapy in patients with Helicobacter pylori infection.

    I.A00-A09.A02   Other salmonella infections

    I.A00-A09.A03   Shigelez

    I.A00-A09.A04   Other bacterial intestinal infections

    I.A00-A09.A05   Other bacterial food poisoning

    I.A00-A09.A08   Viral and other specified intestinal infections

    I.A00-A09.A09   Diarrhea and gastroenteritis of allegedly infectious origin

    IV.E70-E90.E73   Lactose intolerance

    XI.K50-K52.K52   Other non-infectious gastroenteritis and colitis

    XI.K55-K63.K58   Irritable Bowel Syndrome

    XI.K55-K63.K59   Other functional intestinal disturbances

    Contraindications:

    Individual hypersensitivity to the components of the drug.

    Carefully:

    With an increase in the maximum daily dose.

    Pregnancy and lactation:

    The use of the drug during pregnancy and lactation is considered safe, since the drug is not absorbed and does not have a systemic effect.

    Dosing and Administration:

    When acute diarrhea the drug should be taken 1 capsule 4 times a day before the normalization of the stool. Then, the drug should be continued at a dose of 2-3 capsules per day until the symptoms disappear completely.

    For normalization of intestinal microflora and support the immune system, the drug is prescribed in a dose of 2-3 capsules per day for 10-21 days.

    Patients with lactose intolerance it is recommended to take the drug 1 capsule 3 times a day.

    In carrying out eradication therapy the drug is prescribed 2 capsules 2 times a day for two weeks from the first day of eradication therapy.

    Children from 2 years old 1 capsule 2-3 times a day. If the child can not swallow the capsule, it must be opened and mixed with a small amount of liquid.

    Side effects:

    When used in recommended doses according to established indications, side effects were not revealed.

    Overdose:

    Symptoms of overdose have not been registered before. In the case of a significant excess of the recommended dose, medical supervision is advisable.

    Interaction:

    The drug can be used in combination with other medicines. Simultaneous administration with antibiotics is allowed.

    Special instructions:

    Impact on the ability to drive vehicles and manage mechanisms

    The drug does not affect the ability to drive and control machinery.

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