Human immunoglobulin antiresus Rho(D) are used only intramuscularly.
Before the injection, the ampoule with the drug is kept for 2 hours at room temperature (20 ± 2) ° C.To prevent the formation of foam, the drug is drawn into the syringe with a needle with a wide lumen. The drug in the opened ampoule is not subject to storage.
One dose (300 μg) corresponds to 1 ml at a titer of antibodies of 1: 2000 or 2 ml at an antibody titer of 1: 1000.
During pregnancy in Rh-negative women without sensitization phenomena non-specific desensitizing therapy is performed at a period of 10-12, 24-25, 32-33 weeks of gestation. Immunoglobulin human antiresus Rho (D) is administered at a single dose (300 μg) intramuscularly.
When Rh (+) (positive Rh factor) of her husband's blood, the introduction of an immunoglobulin antiresus Rho (D) 300 μg intramuscularly with a period of 28-30 weeks.
Repeated administration of immunoglobulin no later than 48-72 hours after delivery at the birth of a Rh-positive child.
With the artificial termination of pregnancy At a gestation period of more than 13 weeks, a single dose of the drug (300 μg) is recommended. If the pregnancy is interrupted if the period is less than 13 weeks, it is recommended to enter 50 μg of the drug.
When a trauma of the abdominal cavity during the second or third trimester of pregnancy it is recommended to enter one dose of the drug (300 μg).
If a trauma to the abdominal cavity requires the administration of the drug at a period of 13-18 weeks of gestation, another dose (300 μg) should be administered with a gestation period of 26-28 weeks.