Included in the formulation
АТХ:D.11.A.X Other preparations for the treatment of skin diseases
Pharmacodynamics:With external application stimulates the development of granulation tissue and regeneration processes, promotes epithelization; accelerates cleansing, reduces the risk of infection, reduces intoxication of the body, improves the course of the wound process.
Nitrofural is active against gram-positive bacteria: Staphylococcus spp., Streptococcus spp., Bacillus anthracis; Gram-negative bacteria: Escherichia coli, Shigella spp., Salmonella spp. (including Salmonella paratyphi).
Pharmacokinetics:The pharmacokinetics of sodium alginate and calcium gluconate in local application has not been studied. Absorption of nitrofural at local application is insignificant.
Indications:Burns, deep burns with a wet scab and abundant compartments, sluggish after-burn wounds and ulcers, trophic ulcers, pressure sores.
XII.L80-L99.L89 Decubital ulcer
XII.L80-L99.L98.4 Chronic skin ulcer, not elsewhere classified
XIX.T20-T32.T30 Thermal and chemical burns, unspecified
Contraindications:Hypersensitivity, allergic dermatosis, bleeding.
Pregnancy and lactation:There is no information.
The category of FDA recommendations is not defined.
Dosing and Administration:Outwardly: directly on the wound surface (after the toilet wound), the drug is applied so,that the application area should be 0.5-1 cm beyond the affected area; fixed with a bandage or gauze bandage. The bandage is changed as the product dries or dissolves (on average once every 1-3 days). With minor exudation or the beginning of epithelialization, the drug is left on the wound before rejection along with the scab. When compacted crusts are formed in certain areas (because of the non-wetting of the gel), they are removed. The course of treatment - 1-10 dressings.
Side effects:Allergic reactions, dermatitis (2% in persons with psoriasis).
Condensation of the preparation in separate parts of the wound with the formation of a hard-to-detachable crust (for removal, the dressing is wetted with a solution of nitrofural).
Interaction:For the combination is not described.
Sodium alginate is pharmaceutically incompatible with derivatives of acridine, gentian violet, calcium salts, phenylmercury acetate and phenylmercury nitrate, ethanol at a concentration of more than 5% and salts of heavy metals.
Special instructions:The combination in the form of a dosage form is registered only in the territory of the Russian Federation.