Chamomile flowers (Extractum florum Chamomillae officinalis)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Antiseptics and disinfectants

Included in the formulation
  • Azulan
    solution locally inwards externally 
    VIFITEH, CJSC     Russia
  • Romazulan®
    solution locally inwards externally 
    K.O.Biopharm S.A.     Romania
    • АТХ:

    A.01.A.B   Antimicrobials for topical use in diseases of the oral cavity

    Pharmacodynamics:

    Means of plant origin. Contains essential oils - levomenol, bisabolol oxide A, bisabolol oxide B, bisabolone oxide A, camazulene, spatulenol; flavonoids - flavone glycosides, flavonol glycosides, aglycons, including quercetin, isoramnetin, patulein, and also yacedinem, crisospenol, crisosplenetin; hydroxycoumarins, including umbelliferone, herniarin; ramanogalacturonan.

    Reduces the proteolytic activity of pepsin, has an anti-inflammatory effect. Thanks to the presence of camazulene and essential oils, it inhibits lipid peroxidation, which is the reason for the antioxidant effect.

    Has spasmolytic, anti-inflammatory, antimicrobial effect (against Staphylococcus spp. And Candida spp.), Improves tissue regeneration processes. It also has a deodorizing and antipruritic effect.

    Pharmacokinetics:

    Not studied.

    Indications:

    For oral administration: gastritis, duodenitis, peptic ulcer and duodenal ulcer, enterocolitis, flatulence. In the form of microclysters: spastic colitis, hemorrhoids.For topical application: infectious and inflammatory diseases of the ENT organs and oral cavity (pharyngitis, tonsillitis, otitis, stomatitis, gingivitis), infectious and inflammatory diseases of the genitourinary system. For external use: dermatitis, trophic ulcers.

    ICD-10

    I.A00-A09.A04.8   Other specified bacterial intestinal infections

    VIII.H65-H75.H66   Purulent and unspecified otitis media

    IX.I80-I89.I83.2   Varicose veins of the lower extremities with ulcer and inflammation

    IX.I80-I89.I84   Hemorrhoids

    X.J00-J06.J02   Acute pharyngitis

    X.J00-J06.J03   Acute tonsillitis

    XI.K00-K14.K05   Gingivitis and periodontal disease

    XI.K00-K14.K12   Stomatitis and related lesions

    XI.K20-K31.K25   Stomach ulcer

    XI.K20-K31.K26   Duodenal ulcer

    XI.K20-K31.K29   Gastritis and duodenitis

    XII.L20-L30.L20.8   Other atopic dermatitis

    XII.L20-L30.L22   Diaper dermatitis

    XII.L20-L30.L23   Allergic contact dermatitis

    XII.L20-L30.L24   Simple irritant contact dermatitis

    XIV.N30-N39.N30   Cystitis

    XIV.N30-N39.N34   Urethritis and urethral syndrome

    XIV.N70-N77.N76   Other inflammatory diseases of the vagina and vulva

    XVIII.R10-R19.R14   Meteorism and related conditions

    Contraindications:

    Hypersensitivity to chamomile, as well as arnica, yarrow, tansy, wormwood.

    Pregnancy and lactation:The effect during pregnancy and lactation has not been studied.

    The category of the FDA recommendation is not defined.

    Dosing and Administration:

    Apply inside, outwardly, topically. The dosage regimen depends on the indications for use.

    Side effects:

    Allergic reactions.

    Overdose:

    Not described.

    Interaction:

    With the simultaneous application of chamomile and warfarin, it is possible to enhance its effect by keeping hydroxycoumarins in the plant.

    Instructions
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