Poludan® (Poludanum®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbsplyophilizate for the preparation of eye drops
Composition:

Polyriboadenyl acid potassium salt (potassium polyriboadenilate) 0.1 mg, polyribouridic acid potassium salt (potassium polyribouridylate) 0.107 mg.

Excipients: sodium hydrogen phosphate (sodium phosphate 2-substituted) 2.0 mg, potassium dihydrogen phosphate (potassium phosphate 1-substituted anhydrous) 0.408 mg, sodium chloride 8.5 mg.

Description:Liofilizate white.
Pharmacotherapeutic group:immunostimulating agent
ATX: & nbsp
  • Antiviral drugs
    • Pharmacodynamics:

    Poludan® is a biosynthetic polyribonucleotide complex of polyriboadenyl and polyribouridyl acids. Inductor synthesis of endogenous interferon. Has a pronounced antiviral and immunomodulating activity.

    The instillation stimulates the production of endogenous interferon in the serum and tear fluid, which is determined 3 hours after the administration.

    A high level of interferon (110 U / ml in the blood and 75 U / ml in the lacrimal fluid) is maintained by daily administration throughout the course of the course, on the second day after discontinuation of administration is practically not determined (titer does not exceed 10 U / ml). Increases the activity of natural killer cells, initially lowered in patients with ophthalmoherpes, as well as other immunocompetent cells.
    Indications:

    Poludan® is prescribed for adults and children with viral eye diseases: adenoviral andherpetic conjunctivitis, superficial keratoconjunctivitis, keratitis.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Dosing and Administration:

    Locally.

    A solution of Poludan®, intended for instillation into the eye, is prepared by dissolving the contents of the vial in 2 ml of water for injection. The finished solution can be used for 7 days, if stored in a refrigerator.

    Application in adults: Bury in the conjunctival sac 1-2 drops 6-8 times a day. As the inflammation subsides, the number of instillations is reduced to 3-4 times a day.

    Use in children: Bury in the conjunctival sac 1-2 drops 3-4 times a day. As the inflammation subsides, the number of instillations is reduced to 1-2 times a day.

    If there is no effect for 7 days, you should consult a doctor about subconjunctival injections of the drug.

    Side effects:

    Allergic reactions (itching, sensation of foreign body, strengthening conjunctival injection, the emergence of individual follicles in the lower transitional fold).

    Interaction:

    With the simultaneous use of Poludan® with enzyme preparations in connection with the destructive action of enzymeson endogenous interferon, the clinical efficacy of Poludan® is reduced.

    Compatible with antibiotics and medicines for the treatment of viral infections.

    Special instructions:

    Side effects disappear on their own after the drug is discontinued after 1-3 days.

    Form release / dosage:

    Lyophilizate for the preparation of eye drops, 100 units.

    Packaging:

    100 ED in flasks of colorless glass.

    1 or 3 bottles complete with 1 or 3 sterile dropper caps or without them and instructions for use in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of no higher than 8 ° C.

    Keep out of the reach of children.

    Shelf life:4 years.
    Do not use after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LS-002205
    Date of registration:12.03.2012 / 10.11.2014
    The owner of the registration certificate:LENS-PHARM, LLC LENS-PHARM, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp11.02.2016
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