Probiere (Probifor®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspPowder for oral administration.
Composition:
active substance: bifidobacteria sorbed on activated carbon - not less than 500 million colony-forming units (5x108 CFU),

auxiliary substance: lactose monohydrate - up to 0.85 g.
Description:Powder from light gray to dark gray with black coal particles and possible splashes of beige color with a faint smell of fermented milk.
Pharmacotherapeutic group:The medical immunobiological preparation is a probiotic.
ATX: & nbsp
  • Antidiarrhoeal preparations of biological origin regulating the balance of intestinal microflora
    • Pharmacodynamics:
    The antidiarrheal effect of the drug is due to the high concentration of bifidobacteria (Bifidobacterium bifidum No. 1), sorbed on particles of activated carbon, which are antagonists of a wide range of pathogenic (Shigella, Salmonella, Staphylococcus aureus, etc.) and opportunistic microorganisms (proteus, Klebsiella, etc.).

    The anti-infective effect of the drug is enhanced due to the sorption of bifidobacteria on the coal particles, which leads to an accelerated normalization of the gastrointestinal microbiocenosis, activation of the recovery processes in the mucous membranes and an increase in the anti-infective resistance of the organism.

    The antitoxic effect of the drug is provided by: rapid colonization of the intestine with microcolonies of bifidobacteria, restoration of normal microflora,which prevents the penetration of toxins into the internal environment of the body and, being a natural biosorbent, accumulates a significant number of toxic substances that come into the body from outside or form in the body.

    Bifidobacteria in high concentrations activate intestinal parietal digestion, the synthesis of vitamins and amino acids, enhance the protective function of the intestine and the immune defense of the body.
    Indications:
    - diarrhea of ​​different etiology;

    - food poisoning;

    - acute intestinal infections of bacterial and viral origin (salmonellosis, shigellosis, enterocolitis caused by pathogenic representatives of the genus enterobacteria or staphylococci, rotavirus infection) or unidentified etiology;

    - dysbacteriosis of various etiologies, including those that developed on the background and after taking antibiotics; cytostatic, radiation therapy; complicating the course of viral hepatitis, cirrhosis of the liver / diverticulosis of the intestine of various locations;

    - Newborns (including premature) children with a burdened premorbid background, starting from the period of stay in the maternity hospital, to improve the course of the adaptation period, as well as with expressed dysbiosis;

    - pregnant women, in preparation for childbirth, caesarean section and in the postoperative period.

    The drug is used as part of complex therapy

    - chronic infectious and nonspecific inflammatory diseases of the digestive tract (gastroduodenitis, pancreatitis, proctosigmoiditis, colitis, including ulcerative colitis);

    - patients (including newborns) with secondary immunodeficiency states, with severe infectious-inflammatory and purulent-septic diseases (sepsis, peritonitis, etc.), with skin diseases (atopic dermatitis, treptodermia, eczema);

    - irritable bowel syndrome; other functional intestinal disorders;

    - syndrome of disturbed intestinal absorption of various etiologies;

    - acute respiratory viral infections and influenza;

    - surgical patients (including traumatological profile) for preoperative preparation and prevention of postoperative complications; with post-gastrectomy disorders and conditions after cholecystectomy;

    - Oncological patients with chemotherapy, radiation therapy, before and after surgical interventions.
    Contraindications:Congenital insufficiency of lactase. Impaired absorption of glucose-galactose.
    Pregnancy and lactation:The drug is approved for use in women during pregnancy and breastfeeding. There are no special reception conditions.
    Dosing and Administration:
    -In acute intestinal infection, food poisoning, diarrhea:

    - Children up to 6 months of 1 package 2 times a day; children older than 6 months in 1 package 3-4 times a day (possibly with a short interval of 2-3 hours), a course of 2-3 days; with the preservation of clinical symptoms, the course of treatment is extended to 4-5 days;

    - children over 7 years and adults 2-3 packs 2 times a day for 3-5 days;

    - adults of the day of cessation of diarrhea in the early stages of the disease for 3 packages 2 times a day at an interval of 30 minutes - 1 hour; the amount of the drug taken can be increased to 6 packets at a time once a day, a course of 1 to 3 days.

    With chronic pathology of the gastrointestinal tract and functional intestinal disorders - for children and adults, once 3 packages during the evening meal, adults - perhaps 2 packages 2 times a day. The course of treatment is 5-15 days. In severe cases, the amount of medication taken can be increased to children from 1 year and adults to 6 packets per day, and the course to be increased to 30 days.

    With dysbacteriosis of various etiologies, chronic intestinal infections, in patients with immunodeficiency states, with skin diseases, and also to improve the course of adaptation in newborns:

    - premature newborns 1 package 1-2 times per day;

    - full-term newborns and children under 3 years old, 1 package 2 times a day;

    - children from 3 to 7 years - 1 package 3 times a day;

    -to children over 7 years and adults 2-3 packs-2 times a day!

    The course of treatment is 7-10 days.

    In the complex treatment of acute respiratory infections and influenza, patients of all age groups from 1 to 2 days of the disease receive 1 packet 3 times a day. The course of treatment is 2 days.

    Surgical patients, pregnant women in preparation for cesarean section in order to reduce postoperative complications:

    -to the operation for 1 packet 3 times a day for 2-3 days; people with intestinal dysbacteriosis who received antibiotics and chemotherapy, the preoperative course is extended to 7 days;

    - from 2-7 days after the operation, 1 package 3 times a day for 2-3 days, according to the indications -7-10 days.

    Probi® is taken during meals, if necessary, regardless of food intake.The drug before use is mixed with liquid food, preferably a sour milk product, newborns and infants - with mother's milk or a mixture for artificial feeding. You can mix the preparation with 30-50 ml of boiled water at room temperature, and a turbid suspension with black sorbent particles is formed. The resulting aqueous suspension should be drunk without achieving complete dissolution.

    PRECAUTIONS FOR USE

    Precautions are not present.
    Side effects:Not installed.
    Overdose:Cases of overdose were not observed.
    Interaction:With simultaneous reception of ProbiF® with vitamins (especially group B), the effect of the drug is enhanced. When taking antibiotics, the recommended interval between taking the antibiotic and the preparation of ProbiFor® is 3-4 hours.
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the inability to drive vehicles, mechanisms.
    Form release / dosage:Powder for oral administration.
    Packaging:Powder in a package of multilayered metal-polymer material. For 6, 10 or 30 packages with instructions for use in a pack of cardboard
    Storage conditions:
    Store in a dry place at a temperature not exceeding 10 ° C. The lower limit of temperature is not limited.

    KEEP OUT OF THE REACH OF CHILDREN
    Shelf life:
    2 years. Do not use the drug after the expiration date.

    The drug is not suitable for use after the expiry date, with a change in appearance, in the absence or fuzzy marking on the primary packaging, if the primary packaging fails to seal.
    Terms of leave from pharmacies:Without recipe
    Registration number:Р N000090 / 01
    Date of registration:04.09.2011
    The owner of the registration certificate:PARTNER, CJSC PARTNER, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp24.03.2016
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