Probiophore - instructions for use, doses, side effects, contraindications

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Dosage form: & nbspcapsules

Composition:

One capsule contains:

active substance: bifidobacteria B.bifidum, Sorbed on activated carbon - not less than 500 million colony-forming units;

auxiliary substance: lactose monohydrate - up to 0.20 g.

Description:

Capsule № 3 hard gelatinous, cylindrical form with hemispherical ends. The capsule case is white opaque, the lid is yellow opaque. The contents of the capsule are a powder with a weak sour-milk smell from light gray to dark gray with black particles of coal.

Pharmacotherapeutic group:probiotic

ATX: & nbsp

Antidiarrhoeal preparations of biological origin regulating the balance of intestinal microflora

Pharmacodynamics:

The antidiarrheal effect of the drug is due to the high concentration of activated bifidobacteria sorbed on the particles (Bifidobacterium bifidum № 1), which are antagonists of a wide range of pathogenic (Shigella, Salmonella, Staphylococcus aureus, etc.) and conditionally pathogenic microorganisms (proteus, Klebsiella, etc.).

The anti-infective effect of the drug is enhanced by the sorption of bifidobacteria on the particles of coal, which leads to an accelerated normalization of the microbiocenosis of the gastrointestinal tract, activation of the recovery processes in the mucous membranes and an increase in the anti-infective resistance of the organism.

The antitoxic effect of the drug is provided by the rapid colonization of the intestine by the microcolonies of bifidobacteria, the restoration of normal microflora, which prevents the penetration of toxins into the internal environment of the body and, being a natural biosorbent, accumulates a significant number of toxic substances that come into the body from outside or form in the body.

Bifidobacteria in high concentrations activate intestinal parietal digestion, the synthesis of vitamins and amino acids, enhance the protective function of the intestine and the immune defense of the body.

Indications:

- Diarrhea of different etiology; food poisoning; acute intestinal infections of bacterial and viral origin (salmonellosis, shigellosis, enterocolitis caused by pathogenic representatives of the genus enterobacteria or staphylococci, rotavirus infection) or unidentified etiology;

- dysbacteriosis of various etiologies, including those that developed in the background and after taking antibiotics, cytostatic, radiation therapy; complicating the course of viral hepatitis, liver cirrhosis, intestinal diverticulosis of various locations;

- newborns (incl.premature) to children with a burdened premorbid background, from the period of stay in the maternity hospital, to improve the course of the adaptation period, as well as with expressed dysbiosis; pregnant women in preparation for childbirth, caesarean section and in the postoperative period.

The drug is used as part of complex therapy

- chronic infectious and nonspecific inflammatory diseases of the digestive tract (gastroduodenitis, pancreatitis, proctosigmoiditis, colitis, including ulcerative colitis); patients with secondary immunodeficiency states, with severe infectious-inflammatory and purulent-septic diseases (sepsis, peritonitis, etc.); with skin diseases (atopic dermatitis, streptoderma, eczema);

- irritable bowel syndrome; acute respiratory viral infections and influenza;

- surgical patients (including traumatological profile) for preoperative preparation and prevention of postoperative complications; with post-gastrectomy disorders and conditions after cholecystectomy;

- Oncological patients with chemotherapy, radiation therapy, before and after surgical interventions.

Contraindications:

Congenital insufficiency of lactase, impaired absorption of glucose-galactose, hypersensitivity to the components of the drug

Pregnancy and lactation:

Prophyfor ® is approved for use in women during pregnancy and breastfeeding. There are no special reception conditions.

Dosing and Administration:

The drug is used for children from the newborn period and adults.

In case of acute intestinal infection, food poisoning, diarrhea:

- children up to 6 months: 1 capsule 2 times a day; children over 6 months of 1 capsule 3-4 times a day (possibly with a short interval of 2-3 hours), a course of 2-3 days; with the preservation of clinical symptoms, the course of treatment is extended to 4-5 days;

- children over 7 years and adults: 2-3 capsules 2 times a day, treatment course 3-5 days,

- adults to stop diarrhea in the early stages of the disease 3 capsules 2 times a day at intervals of 30 minutes - 1 hour, the dosage can be increased to 6 capsules at a time once a day, the course of treatment 1 to 3 days.

With chronic pathology of the gastrointestinal tract, irritable bowel syndrome - Children 3 capsules once during the evening meal, adults 3 capsules once or 2 capsules 2 times a day.The course of treatment is 5-15 days. In severe cases, the amount of medication taken can be increased to adults and children up to 6 capsules per day, and the course of treatment to be increased to 30 days.

With dysbacteriosis of different etiology, chronic intestinal infections, in patients with immunodeficiency states, with skin diseases, and also to improve the course of adaptation in newborn infants:

- premature neonates: 1 capsule 1-2 times a day;

- term infants and children under 3 years: 1 capsule 2 times a day;

- children from 3 to 7 years: 1 capsule 3 times a day;

- children over 7 years and adults: 2-3 capsules 2 times a day.

The course of treatment is 7-10 days.

In the complex treatment of acute respiratory viral infections and influenza - patients of all age groups with 1-2 days of the disease, 1 capsule 3 times a day. The course of treatment is 2 days.

Surgical patients, pregnant women in preparation for cesarean section in order to reduce postoperative complications:

- before the operation: 1 capsule 3 times a day for 2-3 days; people with intestinal dysbacteriosis who received antibiotics and chemotherapy, the preoperative course is extended to 7 days,

- from 2-7 days after the operation: 1 capsule 3 times a day for 2-3 days, according to the indications - 7-10 days.

Probi® is taken orally during meals, if necessary, regardless of food intake, with water.

Children and patients who can not swallow a whole capsule are opened. The contents of the capsule are mixed with liquid food, preferably a sour-milk product, newborns and infants - with mother's milk or a mixture for artificial feeding.

You can mix the contents of the capsule with 10-50 ml of boiled water at room temperature, and a cloudy slurry with black sorbent particles forms. The resulting aqueous suspension should be drunk without achieving complete dissolution.

Side effects:

Not installed.

Overdose:

Cases of overdose were not observed.

Interaction:

At simultaneous reception with vitamins (especially group B) action of a preparation amplifies.

With simultaneous use with antibiotics, the effect of the preparation Probi® can be reduced - when taking antibiotics, the recommended interval between taking an antibiotic and the preparation of ProbiFor® is 3-4 hours.

Special instructions:

Precautions are not present.

Effect on the ability to drive transp. cf. and fur:

ProbiFore® does not affect the ability to drive vehicles and mechanisms.

Form release / dosage:Capsules, 500 million cfu.

Packaging:

6, 10, 18 or 30 capsules in a jar of polymer material.

The bank with instructions for use is placed in a pack of cardboard.

Storage conditions:

Store at a temperature of 2 to 10 ° C.

Keep out of the reach of children.

Shelf life:

1 year.

Not suitable for use after the expiry date, if external type, in the absence or fuzzy marking, if there is a violation of the integrity of the primary packaging before the first opening.

Terms of leave from pharmacies:Without recipe

Registration number:LS-002558

Date of registration:29.04.2012

The owner of the registration certificate:PARTNER, CJSC PARTNER, CJSC Russia

Manufacturer: & nbsp

PARTNER, CJSC Russia

Representation: & nbspPARTNER CJSC PARTNER CJSC Russia

Information update date: & nbsp29.11.2015

Illustrated instructions

Instructions

Probifor® (Probifor®)