Sulfacil-sodium - instructions for use, dose, side effects, contraindications

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Dosage form: & nbspEye drops.

Composition:

Composition per ml: active substance - sodium sulfacetamide monohydrate (sodium sulfacyl) - 200 mg; Excipients - sodium thiosulfate pentahydrate (sodium sernovatistokisly 5-aqueous), water for injection.

Description:Transparent colorless or slightly yellowish liquid.

Pharmacotherapeutic group:Antimicrobial agent - sulfonamide.

Pharmacodynamics:Sulfatsil sodium - sulfanilamidnye antimicrobial broad-spectrum drugs. Has a bacteriostatic effect. The mechanism of action is associated with a competitive antagonism with para-aminobenzoic acid (PABA) and inhibition digidropteroatsintetazy, which disrupts the synthesis of tetrahydrofolic acid required for the synthesis of purines and pyrimidines. It is active against gram-positive and gram-negative cocci, Escherichia colli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Pharmacokinetics:Penetrates the tissues and fluid eyes. Absorbed into the systemic bloodstream through an inflamed conjunctiva. When applied topically, sulfacetamide maximum concentration in the cornea (about 3 mg / ml), moisture anterior chamber (about 0.5 mg / ml) and iris (about 0.1 mg / ml) is achieved within the first 30 minutes after application. Some amount (less than 0.5 mg / ml) is stored in the eyeball tissues for 3-4 hours. If the damage corneal epithelial penetration sulfacetamide amplified.

Indications:

As part of complex therapy in children and adults with conjunctivitis, blepharitis, with purulent ulcer of the cornea in adults, gonorrhea and chlamydial diseases of the eyes in adults.

Prophylaxis and treatment of blenorea in newborns.

Contraindications:Hypersensitivity to the components of the drug.

Pregnancy and lactation:It is possible to use the prescribing doctor for the treatment of pregnant and lactating mothers if the intended benefit to the mother exceeds the potential risk to the fetus or the baby.

Dosing and Administration:

Adults in the complex therapy: with conjunctivitis, blepharitis, purulent ulcer of the cornea, gonorrheal and chlamydial eye diseases, the drug is instilled in the affected eye 1-2 drops 4-6 times a day. The course of treatment is 7-10 days.

Children in the complex therapy: with conjunctivitis, blepharitis - instill 1 drop into the affected eye 4-5 times a day. The course of treatment is 7-10 days.

For the prevention of blennery, newborns are instilled 1 drop into each eye 3 times at intervals of 10 minutes.

With the treatment of blennorei in newborns instilled 1 drop in the affected eye 4-5 times a day, the course of treatment 7-10 days.

Side effects:With the use of the drug, short-term burning, blurring of vision, lacrimation, redness of the eyes, itching, itching in the eyes, local allergic reactions are possible.

Overdose:

Symptoms: carvings, burning in the eye, red eyes, eyelid edema, lacrimation.

Treatment: withdrawal of the drug, symptomatic treatment.

Interaction:

Co-administration with procaine and tetracaine reduces the bacteriostatic effect of sulvfacetamide. Incompatible with the salts of silver.

Special instructions:

In patients with increased individual sensitivity to furosemide, thiazide diuretics, sulfonylureas or carbonic anhydrase inhibitors, hypersensitivity to sulfacetamide may occur.

If the patient after using the drug temporarily reduces the clarity of visual perception before its recovery is not recommended to drive the car and engage in activities that require increased attention and reactions.

Recommendations for the use of vials with dropper caps: before using the drug, remove the aluminum cap from the bottle, remove the rubber stopper and close the bottle with a dropper, previously released from the package.Then remove the cap from the cap-dropper, turn the bottle, drip the required number of drops of the drug. After applying the bottle, return to the vertical position and put the cap on the lid-dropper.

Recommendations for the use of a tube-dropper (t / k): before using the drug, remove the protective cap, cut off the membrane of the throat of the body with scissors, without damaging the threaded part. Turn the body t / k with the drug throat down and gently move the body t / k, using it as a pipette. After applying the recommended dose of the doctor or specified in the instructions for use of the drug dose, the body t / k turn the threaded part up and screw the protective cap.

Form release / dosage:

Eye drops 20%.

Packaging:

5 ml in bottles of neutral glass, corked with rubber stoppers and rolled with aluminum caps. A bottle together with a lid - a dropper and instruction for use is placed in a pack of cardboard.

By 1 ml or 1.5 ml in a tube-dropper. On 2 or 10 tubes - droppers together with the instruction for use are placed in a pack of cardboard.

Two tubes - droppers are placed in a contour mesh box made of a polyvinylchloride film and aluminum foil.

One contour mesh package together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C. Do not freeze.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N015331 / 01

Date of registration:06.10.2009

The owner of the registration certificate:BELMEDPREPARATY, RUP BELMEDPREPARATY, RUP Republic of Belarus

Manufacturer: & nbsp

BELMEDPREPARATY, JSC Republic of Belarus

Information update date: & nbsp03.09.2015

Illustrated instructions

Instructions

Sulfacyl-sodium (Sulfacyl-sodium)