Iodine (Iodum)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspsolution for external use of alcohol
Composition:

per 1000 ml:

Active substance:

Iodine - 50.0 g
Excipients:

Potassium iodide - 20.0 g
Ethyl alcohol (ethanol) 95% - 416.5 g
Purified water - 519.5 ml
Description:

Transparent liquid of red-brown color with a characteristic smell.

Pharmacotherapeutic group:Antiseptic
ATX: & nbsp
  • Iodine
    • Pharmacodynamics:

    Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect.

    It has a bactericidal effect both on Gram-positive flora (most active on streptococcal flora and Escherichia coli), as well as on pathogenic fungi and yeast. A stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases it disappears. Pseudomonas aeruginosa is stable. The drug is slightly toxic.
    Pharmacokinetics:

    On contact with skin by 30 % turns into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland.Excreted by the kidneys (mainly), intestines, sweat glands. It is excreted in breast milk during lactation.

    Indications:

    Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

    Contraindications:

    Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

    Dosing and Administration:

    External - lubricate the affected or subject to treatment areas of the skin.

    Side effects:

    Skin irritation, allergic reactions (skin itching), with prolonged use on extensive injured surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).

    Overdose:

    Symptoms: inhalation of vapors - defeat of the upper respiratory tract (burn, laryngobrachospasm); when concentrated solutions get inside - severe burns of the digestive tract, development of hemolysis, hemoglobinuria; lethal dose - about 3 g. Treatment: gastric lavage with a 0.5% solution of sodium thiosulfate, intravenously injected sodium thiosulfate 30% to 300 ml.

    Interaction:

    Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed). Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity. Weaken the hypothyroid and strugogenic effects of Li + preparations.

    Special instructions:Very slightly soluble in water (1: 5000), soluble in 10 parts of 95% alcohol, soluble in aqueous solutions of iodides (potassium and sodium). When combined with yellow mercury ointment, the formation of mercury iodide, which has a cauterizing effect, is possible.
    Form release / dosage:

    Solution for external use alcohol 5%.

    Packaging:

    For 10 ml in bottles of glass with a screw mouth, sealed with polyethylene threaded covers (with sealing element and pomazkom, or without anointing).

    By 10, 15, 25 ml into bottles of glass with a screw neck or polymer, Cork sealed with plastic caps and screw-on plastic covers; or sealed with caps screwed on with sealing elements, or capped with polyethylene threaded caps (with sealing element and pomat).

    For 10, 15, 25 ml in the bottles-droppers, ukuporennyh stoppers, droppers and caps screwed or ukuporennye stoppers with screw caps.

    For 10 ml in bottles of a glass tube for medicines (drota), sealed with stoppers or stoppers rubber and aluminum caps.

    Each vial or flask-dropper along with the instruction for use is placed in a pack of cardboard.

    The full text of the instructions for use should be applied to the pack.

    It is allowed to pack bottles or vials without a pack together with an equal number of instructions for use in a group package.

    For 1, 5, 10, 20 liters in a glass bottle with a screw neck, sealed with screwed plastic caps with gaskets. Each glass bottle with a screw neck with instructions for use is placed in a box of corrugated cardboard or plastic (wooden) crate (for hospitals).

    Storage conditions:

    In the dark place at a temperature of at least 0 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:P N003256 / 01
    Date of registration:23.08.2010 / 13.12.2011
    Expiration Date:Unlimited
    The owner of the registration certificate:IVANOVSKAYA Pharmaceutical Factory, OAO IVANOVSKAYA Pharmaceutical Factory, OAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp17.11.2017
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