Clinical and pharmacological group: & nbsp

Genotoninizing agents and adaptogens

Included in the formulation
  • Ladasten®
    pills inwards 
    LEKKO, ZAO     Russia
  • Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):

    ONLS

    АТХ:

    A.13.A   Tetanus preparations

    Pharmacodynamics:

    Increases physical and mental performance, has an anxiolytic, immunostimulating effect. In the central nervous system increases the synthesis of dopamine and stimulates Ca2+-dependent processes of its release. Ability adamantyl bromophenylamine strengthen the synthesis of dopamine de novo fundamentally differentiates the drug from typical psychostimulants. Due to the increased synthesis of dopamine, with the treatment with bromantane, depletion of the neuronal reserves of catecholamines does not develop.

    Reduces the activity of the process of lipid peroxidation, promotes the preservation of the integrity of cell membranes and mitochondria.

    The drug does not have a muscle relaxant and sedative effect.

    The effect of the reception is noted in the very first days. The phenomena of asthenia disappear, physical endurance increases.

    Pharmacokinetics:

    The maximum concentration of the drug in the blood is noted in 2-4 hours after administration. The half-life is 11-12 hours. Metabolized in the liver, eliminated with urine and feces.

    Indications:

    It is used for the treatment of neurotic disorders, for the treatment of asthenic conditions in somatic diseases, and also after the transferred infectious diseases.

    V.F40-F48.F48.0   Neurasthenia

    XXI.Z40-Z54.Z54   Condition of recovery

    Contraindications:Individual intolerance.
    Carefully:

    Use with caution in case of insomnia.

    Pregnancy and lactation:Pregnancy and lactation. Recommendations for FDA - C. Penetrates through the placenta and enters the breast milk.
    Dosing and Administration:

    It is taken orally 50-100 mg 2 times a day. The maximum daily dose is 200 mg.

    Not recommended after 16 hours.

    Duration of treatment: from 2 to 4 weeks.

    The highest single dose: 100 mg.

    The highest daily dose: 200 mg in 2 divided doses.

    Side effects:

    Allergic reactions.

    Increased excitability of the central nervous system, insomnia.

    Overdose:

    With a significant overdose develops drowsiness, adynamia.

    Treatment: nonspecific detoxification therapy.

    Interaction:

    The effectiveness of the action does not depend on the intake of food.

    The drug lowers the hypnotic effect of sodium thiopental.

    It does not relieve the anxiolytic effects of benzodiazepine derivatives.
    Special instructions:

    Adamantyl bromophenylamine is used to improve the general condition during convalescence after severe infections and somatic diseases.

    It is successfully used for organic brain lesions and chronic fatigue syndrome.

    Does not cause addiction and drug dependence.

    In sleep disorders, the drug is not required to be withdrawn, it is sufficient to adjust the dose and time of administration.

    In sports medicine is considered doping.

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