Adrianol® (Adrianol®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspnasal drops [for children]
Composition:1 ml of the solution contains:

Active substances: phenylephrine hydrochloride 0.5 mg, lerimazoline hydrochloride 0.5 mg.

Excipients: methylcellulose 10000 1.32 mg, benzalkonium chloride 0.20 mg, glycerol 0.015 mg, citric acid monohydrate 5.72 mg, sodium hydrogen phosphate dihydrate 8.11 mg, water purified to 1.00 ml.
Description:

Transparent, colorless or slightly yellowish solution.

Pharmacotherapeutic group:Antitussive medication - alpha-adrenomimetic
ATX: & nbsp
  • Phenylephrine
    • Pharmacodynamics:Phenylephrine and Lerimazoline are vasoconstrictors that have an anti-edematous effect on the nasal mucosa during topical application. Reducing edema of the mucosa leads to normalization of the nasal breathing and pressure reduction in paranasal sinuses and middle ear. The viscous consistency of the solution increases duration of action of the drug.
    Indications:

    Acute and chronic rhinitis, sinusitis,

    It is used as an auxiliary decongestant during diagnostic procedures and surgical manipulations.

    Contraindications:

    Increased individual sensitivity, thyrotoxicosis, pheochromocytoma, glaucoma, severe kidney damage, arterial hypertension, ischemic heart disease, atrophic rhinitis, general atherosclerosis, children under 3 years.

    Carefully:Due to the content of ethanol, caution should be exercised when assigning it to patients: with liver, brain, alcoholism, epilepsy, as well as children, pregnant and lactating.
    Dosing and Administration:

    Children from 3 years: 2 drops in each nasal passage 3 times a day.

    The duration of the drug is not more than one week, then a break for several days is necessary.
    Side effects:

    Burning, soreness or dryness of the nasal mucosa, swelling of the mucous membrane of the nasal cavity, abundant discharge, nausea, dizziness, headache, violation of taste sensitivity, tachycardia, increased blood pressure (BP), allergic reactions. With prolonged use - rhinitis, nasal congestion, atrophy of the nasal mucosa.

    Overdose:

    Symptoms: fatigue, dizziness, nausea, insomnia, increased blood pressure, tachycardia, fever, shock, reflex bradycardia.

    Interaction:

    In combination with antidepressants and monoamine oxidase (MAO) inhibitors, the risk of hypertension is increased.

    Special instructions:

    Do not use simultaneously with MAO inhibitors and within 10 days after the end of their use.With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), so do not use for a long time, for example, in chronic rhinitis.

    Form release / dosage:

    Nasal drops [for children].

    Packaging:

    10 ml per drop bottle of high-density polyethylene with a screw cap made of high-density polyethylene. 1 bottle with instructions for use in a cardboard box.

    Storage conditions:

    In dry, dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children!

    Shelf life:

    3 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:On prescription
    Registration number:П N013655 / 02
    Date of registration:14.03.2008/09.03.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:Zdravle-Leskovac HFZ, AOZdravle-Leskovac HFZ, AO Serbia
    Manufacturer: & nbsp
    Representation: & nbspACTAVIS GROUP AO ACTAVIS GROUP AO Iceland
    Information update date: & nbsp04.02.2017
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