Alflutop (Alflutop)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspinjection
Composition:

The active component of the drug is bioactive concentrate from small marine fish (Kilka (Sprattus sprattus sprattus); Merlang the Black Sea (Odontogadus merlangus euxinus), Black Sea Bucket (Alosa tanaica nordmanni), Anchovy Black Sea (Engraulis encrassicholus ponticus)), obtained by extraction with subsequent deproteinization and delipidization.

Composition of the preparation per 1 ml:

active substance: bioactive concentrate 0.1 ml;

Excipients: phenol (max 0.005 g), water for injection (up to 1 ml).

Description:

Colorless or slightly brownish-yellow, or slightly yellow cyst, a clear liquid.

Pharmacotherapeutic group:tissue repair stimulator of natural origin
ATX: & nbsp
  • Other drugs for the treatment of diseases of the musculoskeletal system
    • Pharmacodynamics:

    Alflutop is a chondroprotector, the active component of which is the bioactive concentrate from small marine fish. The concentrate contains mucopolysaccharides (chondroitin sulfate), amino acids, peptides, sodium, potassium, calcium, magnesium, iron, copper and zinc ions.

    Alflutop prevents the destruction of macromolecular structures of normal tissues, stimulates the recovery processes in interstitial tissue and articular cartilage tissue, which explains its analgesic effect. Anti-inflammatory action and tissue regeneration are based on inhibition of hyaluronidase activity and normalization of biosynthesis of hyaluronic acid.Both of these effects are synergistic and cause the activation of restorative processes in the tissues (in particular, the restoration of the cartilage structure).

    Indications:Alflutop is used in adults with primary and secondary osteoarthrosis of different localization (coxarthrosis, gonarthrosis, arthrosis of small joints), osteochondrosis and spondylosis.
    Contraindications:

    Hypersensitivity to the components of the drug.

    Pregnancy and lactation.

    Childhood.

    It is not recommended to prescribe the drug in adolescence because of the lack of scientific, clinical data in this category of patients.

    Dosing and Administration:

    With polyostoarthrosis and osteochondrosis the drug is administered intramuscularly 1 ml per day. The course of treatment is 20 injections (1 injection per day for 20 days).

    With the primary lesion of large joints the drug is administered intra-articularly in 1-2 ml in each joint with an interval of 3 4 days. Blows on the course of 5-6 injections in each joint.

    A combination of intraarticular and intramuscular injection methods is possible.

    The course of treatment should be repeated 6 months after the doctor's consultation.

    Side effects:

    Rarely, itching dermatitis, reddening of the skin and a burning sensation at the injection site, short-term myalgia.

    In some cases, with intra-articular injections, there may be a transient increase in the pain syndrome.

    It is very rare to develop anaphylactic reactions.

    Overdose:

    In case of an overdose in predisposed patients, allergic reactions (sometimes severe) may occur.

    Interaction:

    So far, not identified.

    Special instructions:

    In the case of individual intolerance to seafood (sea fish), the risk of allergic reactions increases.

    Form release / dosage:Injection.
    Packaging:

    1 ml or 2 ml in ampoules of dark glass with a white break ring, or 2 ml in prefilled syringes with a capacity of 2.25 ml of colorless glass.

    A label is affixed to each ampoule or pre-filled syringe.

    For 5 ampoules in a cell polymer package with a coating of aluminum foil or 1 pre-filled syringe in a cellular polymer package coated with aluminum or paper-polyethylene foil.

    By 2 (1 ml ampoules) or 1 (2 ml ampoules), the cell packs together with the instructions for use in a pack of cardboard,or 5 (pre-filled 2 ml syringes) of the cell packs with an equal number of disposable needles together with instructions for use in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of 15 to 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use the drug with expired shelf life.

    Terms of leave from pharmacies:On prescription
    Registration number:П N012210 / 01
    Date of registration:09.07.2007 / 01.11.2012
    The owner of the registration certificate:K.O. Biotekhnos SAK.O. Biotekhnos SA Romania
    Manufacturer: & nbsp
    Representation: & nbspLABMGMU, LLCLABMGMU, LLCRussia
    Information update date: & nbsp21.03.2016
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