Allochol (Allochol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspfilm-coated tablets
Composition:

One tablet contains:

Active components: bile dry with cholic acid content - 80 mg, with a content of cholic acid of at least 30 mg, garlic dried, powder - 40 mg, leaves nettle netted - 5 mg, charcoal activated - 25 mg;

Excipients: cellulose microcrystalline - 212.9 mg, sodium croscarmellose - 11.4 mg, silicon dioxide colloidal anhydrous -1,9 mg, magnesium stearate - 3.8 mg.

Film coating: White coating colors: hypromelose, titanium dioxide (E 171), polyethylene glycol (macrogol, PEG 400) - 12.5 mg;

Yellow coating: Polyvinyl alcohol, talc, titanium dioxide (E171), polyethylene glycol (macrogol, PEG 4000), lecithin, quinoline yellow (E 104), indigo carmine (E 132) - 12.5 mg.

Description:The tablets, covered with a film coating, are from yellow to greenish-yellow in color, round in shape with a biconvex surface. On the cross section, the core is visible, surrounded by a layer of shell.
Pharmacotherapeutic group:Cholagogue
ATX: & nbsp
  • Other drugs for the treatment of bile duct diseases
    • Pharmacodynamics:

    Combination drug, enhancing the formation of bile and bile acids. The action of bile is caused by the reflex influence on the secretory function of the liver parenchyma. Bile strengthens also the secretory and motor functions of the gastrointestinal tract.

    Substances contained in garlic, enhance the secretory and motor function of the gastrointestinal tract, stimulate the secretion of bile.

    Nettle leaves have cholagogue and anti-inflammatory properties.

    Activated carbon is an adsorbent that binds a zoxic substance in the gastrointestinal tract.

    Pharmacokinetics:

    The drug is well absorbed in the intestine. Cholic and chenodeoxycholic acid, contained in bile, undergo 7α-dehydroxylation in the intestine. Chenodeoxycholic acid, in addition, is metabolized in the liver: conjugated to amino acids, secreted in bile, whence it is again released into the intestine, then partially reabsorbed; the rest is excreted with feces. Pharmacokinetic parameters of biologically active substances of garlic and nettle leaves have not been studied in view of the complexity of their composition.

    Activated charcoal from the intestine is not absorbed and is completely eliminated with calves in 7-10 hours. Activated carbon is non-toxic, well excreted from the body. Cal after the drug is painted black.
    Indications:

    As part of complex therapy:

    - chronic of the stone (non-calculous) cholecystitis;

    - hypokinetic (hypomotor) biliary dyskinesia;

    - postcholecystectomy syndrome;

    - atonic constipation;

    - nonspecific reactive hepatitis;

    - cholangitis.

    Contraindications:

    - Hypersensitivity to the components of the drug;

    - hyperkinetic (hypermotor) biliary dyskinesia;

    - acute hepatitis;

    - acute and subacute liver dystrophy;

    - obstructive jaundice;

    - ulcerative stomach disease and duodenal ulcers in the phase of exacerbation;

    - acute enterocolitis;

    - calculous cholecystitis;

    - acute pancreatitis;

    - age to 18 years.

    Carefully:- Urolithiasis disease.
    Pregnancy and lactation:The use of the drug during pregnancy and during breastfeeding is possible if the expected benefit for the mother exceeds potential risk to the fetus and the baby. Consultation of the doctor is necessary.
    Dosing and Administration:

    Is taken orally after a meal. Adults - 1-2 pills 3-4 times a day. Course of treatment - 3-4 of the week. When the disease worsens, the 1 tablet 2-3 times a day for 1-2 months.Repeated courses of treatment are conducted with an interval of 3 months.

    Side effects:

    - Allergic reactions are possible;

    - diarrhea.

    If any of the instructions specified in the instruction side effects are aggravated, or you noticed any other side effects specified in the instructions, report it doctor.

    Overdose:

    To date, cases of overdose not registered, with prolonged use in doses exceeding the recommended, the following symptoms are possible: diarrhea, nausea, pruritus, an increase in the level of transaminases in the blood. Treatment: withdrawal of the drug, symptomatic therapy, there is no specific antidote.

    Interaction:

    Simultaneous application of Allochol with synthetic or vegetable choleretics of origin strengthens bile formation; combination of the drug with laxatives drugs leads to the elimination of constipation; the drug improves absorption fat-soluble vitamins; using Allocha with antiseptics or chemotherapeutic agents for infectious processes in the liver or biliary tract. ways to improve therapeutic effectiveness the latter.

    Preparations containing aluminum hydroxide, colestyramine, colestipol reduce absorption and reduce the effect - simultaneous administration is not appropriate.

    Special instructions:Not described.
    Effect on the ability to drive transp. cf. and fur:

    The use of the drug has no effect on ability to perform potentially of hazardous activities requiring increased concentration and speed of psychomotor reactions (vehicle management, work with moving mechanisms).

    Form release / dosage:Film-coated tablets.
    Packaging:For 10 or 50 tablets covered with a film sheath, in a blister pack of 5 blisters of 10 tablets coated with a film sheath, or 1 blister of 50 tablets coated with a film sheath, together with a medical instruction, put in a pack of cardboard.
    Storage conditions:

    Store in a dry place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    4 years.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-006075/08
    Date of registration:31.07.2008 / 12.12.2012
    Expiration Date:Unlimited
    The owner of the registration certificate:BORSHAGOVSKY HFZ NPC, CJSCBORSHAGOVSKY HFZ NPC, CJSC Ukraine
    Manufacturer: & nbsp
    Information update date: & nbsp11.07.2017
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