Clinical and pharmacological group: & nbsp

Mucolytics and stimulators of motor function of the respiratory tract

Included in the formulation
АТХ:

R.05.C.A   Expectorants

R.05.C.A.10   Combination of expectorants

Pharmacodynamics:

Combined drug for treating cough, has mucolytic and expectorant effect, and also has anti-inflammatory activity.

Ambroxol has secretory, secretory and expectorant action, normalizes the disturbed ratio of serous and mucous components of sputum, increases the secretion of surfactant in the alveoli. Reduces the viscosity of sputum and promotes its spillage.

Glycyrrhate (glycyrrhizic acid and its salts) has anti-inflammatory and antiviral effects. Has a cytoprotective effect due to antioxidant and membrane-stabilizing activity. Potentiates the action of endogenous glucocorticosteroids, providing anti-inflammatory and anti-allergic action. Due to its pronounced anti-inflammatory activity, it helps to reduce the inflammatory process in the respiratory tract.

Extract of herb thyme contains a mixture of essential oils, which have an expectorant and anti-inflammatory effect.In addition, the herb extract of thyme has weak spasmolytic and reparative properties.

Pharmacokinetics:Data not provided.
Indications:Diseases of the respiratory tract with the formation of viscous sputum: acute and chronic bronchitis, pneumonia, chronic obstructive pulmonary disease, bronchiectatic disease.

X.J10-J18.J18.9   Pneumonia, unspecified

X.J20-J22.J20.9   Acute bronchitis, unspecified

X.J20-J22.J22   Acute respiratory infection of lower respiratory tract, unspecified

X.J40-J47.J42   Chronic bronchitis, unspecified

X.J40-J47.J44.9   Chronic obstructive pulmonary disease, unspecified

X.J40-J47.J47   Bronchoectasia

XVIII.R00-R09.R09.3   Sputum

Contraindications:Hypersensitivity, pregnancy, lactation, children under 2 years.
Carefully:Hepatic, renal failure, peptic ulcer of the stomach and duodenum, bronchial asthma.
Pregnancy and lactation:The category of FDA recommendations is not defined. Adequate and well-controlled studies on humans have not been conducted. Contraindicated in pregnancy and lactation.
Dosing and Administration:Inside, during a meal, with a small amount of water.Adults and children over 12 years of age - 10 ml 4 times a day. Children 2-6 years - 2.5 ml 3 times a day; 6-12 years - 5 ml 3 times a day.
Side effects:

Allergic reactions.

Rarely - weakness, headache, diarrhea, dry mouth and respiratory tract, exanthema, rhinorrhea, constipation, dysuria. With prolonged use in high doses - gastralgia, nausea, vomiting.

Overdose:

Nausea, vomiting, diarrhea, indigestion.

Treatment: induction of vomiting, gastric lavage in the first 1-2 hours after taking the drug.

Interaction:Joint use with antitussive drugs leads to difficulty in sputum discharge.
Special instructions:Do not use without medical appointment for more than 5 days. When prescribing a drug to a diabetic patient, remember that 5 ml of syrup contains sorbitol in an amount corresponding to 0.18 XE.
Instructions
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