Amizon® (Amizon)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceEnisamia iodideEnisamia iodide
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  • Amizon®
    pills inwards 
    FARMAK, PAO     Ukraine
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    AVEKSIMA, JSC     Russia
  • Nobasite®
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    • Dosage form: & nbspfilm-coated tablets
    Composition:

    1 the tablet contains:

    active substance: Amizon® (Enisamia iodide) 0.250 g;

    Excipients: lactose monohydrate (200) 0.011 g, cellulose microcrystalline 101-0.021 g, povidone K-17 0.009 g, croscarmellose sodium 0.006 g, calcium stearate 0,003 g, OPADRY II 85 F Clear 0.010 g (polyethylene glycol 0.0015 g, polysorbate 80-0. 0003 g, alcohol polyvinyl - 0.0052 g, talc - 0.003 g).

    Description:

    Tablets of round shape, biconvex, yellow or yellow-green color, covered with a film membrane. Presence of insignificant inclusions is allowed on the surface.

    Pharmacotherapeutic group:Antiviral agent
    ATX: & nbsp

    J.05.A.X   Other antiviral drugs

    Pharmacodynamics:

    Amizon® is an antiviral agent derived from isonicotinic acid. Effectively suppresses the effect of influenza viruses and other pathogens of acute respiratory viral infections due to direct (inhibitory) effect on the penetration of viruses through the cell membrane.

    Has interferonogenic properties, promotes an increase in the concentration of endogenous interferon (interferon alfa and interferon gamma) in blood plasma in 3-4 times.

    Increases the resistance of the body to viral infections.

    Reduces acute clinical manifestations of viral intoxication, contributes to reducing the duration of the disease.

    Pharmacokinetics:

    After ingestion, Enisamium iodide quickly enters the blood, the maximum concentration in the blood is observed after 2-2.5 hours. The half-life period is 13.5-14 hours, metabolized in the liver, but quickly removed from the tissues (half-life is 2-3 hours). It is excreted from the body by 90-95% with urine in the form of metabolites.

    Indications:Treatment of influenza and other acute respiratory viral infections, including in the complex therapy.
    Contraindications:

    Hypersensitivity to any of the components of the drug. Deficiency of lactase, lactose intolerance, glucose-galactose malabsorption.

    Children under 18 years of age, pregnancy, lactation.

    The presence of allergic reactions regardless of the nature of the allergen in the anamnesis.

    Heavy organic lesions of the liver and kidneys.

    Pregnancy and lactation:

    It is not recommended to use during pregnancy and lactation.

    Dosing and Administration:

    Treatment begins when the first signs of the disease appear.

    Amizon® is taken orally after a meal, without chewing on 0.5 g 3 times a day. The maximum single dose is 1 g, the daily dose is 2 g.

    The recommended course of treatment is 5 to 7 days.

    If the health deteriorates or does not improve within 3 days, a doctor's consultation is necessary.

    Side effects:

    Allergic reactions: hypersensitivity reactions, including skin rashes, hives, angioedema, itching.

    On the part of the digestive system: dryness and bitter taste in the mouth, swelling of the oral mucosa. hypersalivation, staining of the tongue in yellow, nausea, vomiting, heartburn, abdominal pain, heaviness in the right hypochondrium, diarrhea, bloating.

    From the respiratory system: shortness of breath, irritation of the throat.

    In the post-marketing period in single cases, the following adverse reactions were noted: headache, dizziness, weakness, fluctuations in blood pressure. If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

    Overdose:

    When an overdose of the drug may increase the manifestations of side effects, described in the relevant section.When they appear, gastric lavage is performed, symptomatic treatment.

    Interaction:

    Interaction with other drugs is not sufficiently studied.

    Amizon increases the effect of antibacterial and immunomodulating agents. It is advisable to combine this drug with ascorbic acid and other vitamins. Also, Amizon can be administered concomitantly using recombinant interferon.

    Special instructions:

    Caution should be used to prescribe the drug to patients with thyroid disease, especially with hyperthyroidism.

    Effect on the ability to drive transp. cf. and fur:

    The administration of Amizon® does not affect the ability to drive transport and various mechanical equipment.

    Form release / dosage:

    Tablets coated with a film coat of 0.25 g.

    Packaging:

    For 10 or 20 tablets in a blister pack. For 1 or 3 blisters (10 tablets), together with instructions for medical use, put in a pack of cardboard.

    For 1 blister (20 tablets each), along with the instructions for use are placed in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-000230
    Date of registration:16.02.2011 / 20.02.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:FARMAK, PAO FARMAK, PAO Ukraine
    Manufacturer: & nbsp
    Representation: & nbspFARMAK PAOFARMAK PAO
    Information update date: & nbsp22.07.2017
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