Antigrippin maximum (Antigrippin-maximum)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbsp

powder for solution for oral administration [lemon, lemon with honey, raspberry, black currant]

Composition:

Active substances: paracetamol - 360 mg, ascorbic acid 300 mg, calcium gluconate monohydrate - 100 mg, rimantadine hydrochloride - 50 mg, rutozide (rutin) - 20 mg, loratadine - 3 mg;

auxiliarysubstances: aspartame - 30 mg, gpromellose - 10 mg, silica dioxide countloid - 20 mg, lactose - 4086 mg, aromafood processor [lemon or lemon with mehouse, or crimson, or blackcurrant] - 21 mg.

Description:

The contents of the sachet - mixture of granules of almost white color with a powder of yellowish-greenish color with a characteristic smell (lemon, lemon with honey, raspberry, black currant).

Solution after dissolving the powder - colorless or with a yellowish hue, a slightly cloudy solution with a characteristic smell (lemon, lemon with honey, raspberries, black currant). Presence of undissolved yellow particles is allowed.

Pharmacotherapeutic group:ORZ and "colds" of symptoms remedy
ATX: & nbsp
  • Other combined drugs used for catarrhal diseases
    • Pharmacodynamics:

    The combined preparation possesses antiviral and interferonogenic, antipyretic, anti-inflammatory, analgesic, antihistaminic, angioprotective action.

    Paracetamol has antipyretic, anti-inflammatory and analgesic effect.

    Ascorbic acid participates in the regulation of redox processes, carbohydrate metabolism, capillary permeability, coagulation, tissue regeneration, activates immune responses.

    Calcium gluconate monohydrate It prevents the development of increased vascular permeability and fragility, causing the hemorrhagic processes for influenza and acute respiratory viral infections (ARVI) and restores the capillary blood circulation, anti-allergic action.

    Rimantadine hydrochloride has antiviral activity against influenza virus type A (especially A2), reduces the toxic manifestations caused by influenza viruses of other types and viruses causing SARS. Has pronounced interferonogenic properties, increasing the total content of interferons and especially interferon-gamma in blood enhances the protective properties of the drug against viral infection, damaging the respiratory tract.

    Rutozid (rutin) is an angioprotector. Reduces the permeability of capillaries, swelling and inflammation, strengthens the vascular wall.It inhibits aggregation and increases the degree of erythrocyte deformation.

    Loratadin has a pronounced antihistamine effect, prevents the development of edema of the tissues associated with the release of histamine.

    Indications:

    Etiopathogenetic and symptomatic treatment of influenza, acute respiratory viral infection, feverish conditions due to viral respiratory tract infection in adults and children over 12 years of age.

    Contraindications:

    Hypersensitivity to one or more of the components that make up the drug; erosive and ulcerative lesions of the gastrointestinal tract in the phase of exacerbation; gastrointestinal bleeding; hemophilia; hemorrhagic diathesis; hypoprothrombinemia; portal hypertension; avitaminosis K; kidney failure; pregnancy, lactation; thyrotoxicosis, acute kidney disease, liver (acute glomerulonephritis, acute pyelonephritis, acute hepatitis, or exacerbation of chronic diseases of these organs); chronic alcoholism. Restriction of use in epilepsy, cerebral atherosclerosis.

    Dosing and Administration:

    Inside.

    Dissolve the contents of one sachet in 1 glass of boiled hot water. To use in a hot kind. Stir the solution before use.

    Adults and children over 12 years: take one packet, 2-3 times a day after meals, for 3-5 days (not more than 5 days), until the symptoms disappear.

    If within 3 days after the beginning of taking the drug there is no improvement in the state of health, the drug should be stopped and consult a doctor.

    Side effects:

    In accordance with the constituent components.

    From the side of the central nervous system. Rarely increased excitability, tremor, hyperkinesia.

    From the gastrointestinal tract. With a duration of intake of more than 7 days, possible damage to the mucous membrane of the stomach and duodenum, dyspepsia, dry mouth, anorexia, flatulence, diarrhea.

    From the side of the blood system. In particular, with the duration of admission more than 7 days, agranulocytosis, leukopenia, thrombocytopenia, neutropenia, anemia.

    Allergic reactions. Rarely, skin rash, itching, hives are possible.

    In case of symptoms of side effects, stop taking this medication immediately and consult a doctor.

    Overdose:

    Symptoms: in the first 24 hours, paleness, nausea, vomiting and pain in the epigastric region, tremor, drowsiness, tachycardia, increased bilirubin in the blood, metabolic disorders, exacerbation of concomitant chronic diseases are possible.

    Treatment: induce vomiting reflex, gastric lavage, intake of adsorbents, symptomatic therapy.

    It is necessary to consult a doctor.

    Interaction:

    If you need to share with other medications, consult your doctor.

    It is not recommended to appoint with anticoagulants, glucocorticoid drugs, hepatotoxic agents, barbiturates, anticonvulsants, rifampicin, alcohol.

    With simultaneous administration with metoclopramide, an increase in absorption is possible.

    With simultaneous application with coumarin derivatives, it is possible to develop a small hypoprothrombinemia.

    Special instructions:

    Duration of application - no more than 5 days. With long-term use (more than 7 days), an exacerbation of chronic comorbidity may occur, in elderly patients with hypertension, the risk of hemorrhagic stroke increases (due to which is part of the preparation of rimantadine hydrochloride).

    Do not use if there are metastatic tumors.

    Do not administer to children under 12 years of age.

    Form release / dosage:Powder for solution for oral administration.
    Packaging:

    For 5 grams of powder to make a solution for ingestion [lemon or lemon with honey, or raspberry, or black currant] in bags heat-sealable.

    3, 6, 8, 12 or 24 bags with instructions for use in a pack of cardboard.
    Storage conditions:

    In a dry, protected from light place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-002564/08
    Date of registration:07.04.2008 / 04.05.2017
    Expiration Date:Unlimited
    The owner of the registration certificate:Anvilab, OOO Anvilab, OOO Russia
    Manufacturer: & nbsp
    Representation: & nbspAnviLab Ltd AnviLab Ltd Russia
    Information update date: & nbsp06.09.2017
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