Clinical and pharmacological group: & nbsp

Other synthetic antibacterial agents

Included in the formulation
  • Osarbon®
    suppositories the vagina. 
    NIZHFARM, JSC     Russia
  • АТХ:

    G.01.A.B   Arsenic compounds

    Pharmacodynamics:

    The drug with antiprotozoal, antibacterial and anti-inflammatory action for topical application.

    Acetarsol contains about 27% arsenic. Due to its ability to block sulfhydryl enzyme systems, it breaks the metabolic processes of the protozoa (including trichomonads, amoebae), and some spirochetes.

    Pharmacokinetics:

    The drug acts locally, almost does not have a resorptive effect.

    Indications:

    Trichomonas colpitis.

    I.A50-A64.A59.0   Urogenital trichomoniasis

    Contraindications:

    Hepatic failure, chronic renal failure, diabetes, hemorrhagic vasculitis, tuberculosis, hypersensitivity to acetarosol, heart and gastrointestinal disease, pregnancy.

    Carefully:

    When using acetazol, as well as other drugs of arsenic, you can not exclude the development of jaundice and hepatitis.

    Pregnancy and lactation:

    Category of recommendations Food and Drug Administration (US Food and Drug Administration) not determined.

    When pregnancy is contraindicated. Adequate and well-controlled studies on humans and animals have not been conducted.

    Dosing and Administration:

    Intravaginally, as part of vaginal suppositories at a dose of 0.25 g once a day.

    Side effects:

    Possible: jaundice, hepatitis, polyneuritis, vomiting, diarrhea, fever, dermatitis, allergic reactions.

    Overdose:

    There is no evidence of an overdose of the drug.

    Interaction:

    Drug interaction of the drug has not been described to date.

    Special instructions:

    Intravaginally can be used in combination with boric acid.

    In some cases, used internally to treat intestinal amebiasis during remission.

    When using acetazol as well as other arsenic preparations, one can not exclude the development of jaundice, hepatitis, polyneuritis.

    Instructions
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