Included in the formulation
Pharmacodynamics:The pharmacological action is gestagenic.The drug has a high progestogenic activity, similar to the action of progestins. Causes the transition of the uterine mucosa from the proliferation phase, stimulated by the follicular hormone, into the secretory phase; promotes the development of a fertilized egg; reduces the excitability and contractility of the musculature of the uterus and fallopian tubes, activates the formation of the end elements of the breast.
Pharmacokinetics:There is no data on the pharmacokinetics of the drug.
Indications:Habitual and threatening miscarriages in the first trimester of pregnancy, menstrual irregularities, contraception.
XIV.N80-N98.N93 Other abnormal bleeding from the uterus and vagina
XIV.N80-N98.N94.6 Dysmenorrhea, unspecified
XV.O20-O29.O20.0 Threatening abortion
XV.O00-O08 Pregnancy with abortive outcome
XXI.Z30-Z39.Z30 Monitoring the use of contraceptives
Contraindications:Neoplasms, liver dysfunction, increased blood coagulability.
Carefully:Diseases of the liver and gallbladder, epilepsy, depression, ulcerative colitis, uterine myoma, mastopathy, tuberculosis, kidney disease, adolescence (without regular ovulatory cycles).
Pregnancy and lactation:Action category for the fetus by Food and Drug Administration (US Food and Drug Administration) - H.
In the absence of two consecutive menstrual cycles, you should cancel the appointment and exclude pregnancy. If the scheme of taking the drug is violated, pregnancy should be excluded after the first absent cycle. After the withdrawal of funds in order to attempt to become pregnant, you should take a break for 1-2 months or wait for regular menstruation.
Penetrates into breast milk. Depending on the type of drug and dosage regimen, it can increase, decrease or not affect the quality and quantity of milk. It is not recommended to use high doses during the period of breastfeeding (treatment is started after lactation is established).
Dosing and Administration:Inside, regardless of food intake.
At a threatening miscarriage - 0.0005-0.001 g 1-3 times a day for 7-10 days. With the usual miscarriage - 0.0005-0.002 g for 1-2 months (course - 0.003-0.006 g).
With dysfunctional uterine bleeding - 0.0005-0.0025 g per day from the 15th to the 24th day of the cycle.
For contraception - 0.0005 g per night (for not more than 1 year).
Side effects:Insomnia, nausea, headache, breast engorgement, allergic reactions (urticaria).With pronounced side effects, the drug is canceled.
Overdose:Nausea, vomiting.
Treatment is symptomatic.
Special instructions:Duration of treatment - no more than 1 year.