Aurobin® (Aurobin®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspointment for rectal and external use
Composition:

1 g of ointment contains:

Active substances:

Prednisolone capronate 0.002 g,

Lidocaine hydrochloride - 0.020 g;

Dexpanthenol - 0.020 g.

Excipients:

Polysorbate 60 0.001 g, triclosan 0.001 g, methyl parahydroxybenzoate 0.002 g, cetyl alcohol 0.010 g, glycerol 0.015 g, propylene glycol 0.020 g, macrogol stearate 0.050 g, paraffin liquid 0.050 g, dimethicone 0.05 g , neutral oil - 0.060 g, stearic acid - 0.080 g, purified water - 0.620 g.

Description:Homogenous ointment is white or almost white, almost odorless.
Pharmacotherapeutic group:Glucocorticosteroid combination for topical use
ATX: & nbsp
  • Prednisolone in combination with other drugs
    • Pharmacodynamics:

    Aurobin® is a combined preparation for the treatment of inflammatory diseases of the anogenital region.

    Prednisolone caprolate is a non-halogenated glucocorticosteroid. Has local anti-allergic and anti-inflammatory effect. The drug reduces the permeability of blood vessels, increases the tone of the walls of blood vessels, reduces the symptoms of inflammation.

    Lidocaine - local anesthetic, quickly eliminates pain and burning sensation.

    Dexpanthenol - promotes the regeneration of the affected epithelium and mucous membrane.

    Triclosan is an antiseptic broad-spectrum agent that acts on bacteria and fungi.

    Pharmacokinetics:Not studied.
    Indications:

    Processes accompanied by inflammation of the perianal area, an itch of the anus, eczema and dermatitis of the perianal area, cracks, hemorrhoids, fistula of the anus.

    Contraindications:

    Hypersensitivity to the components of the drug.

    The drug can not be used to treat the eyes or periorbital area.

    Bacterial, viral or fungal skin infections.

    Simultaneous use of lidocaine for other indications.

    Children up to 1 year.

    Pregnancy and lactation:

    There is insufficient data on the safe use of the drug in pregnant women, so the drug can not be used in the first trimester of pregnancy. In the second and third trimester of pregnancy, when prescribing a drug, it is necessary to carefully evaluate the relationship between benefit and risk.

    Lactation period:

    Corticosteroids and lidocaine penetrate into the mother's milk, so during lactation it is necessary to resolve the issue of stopping breastfeeding.

    Dosing and Administration:

    Externally, rectally.

    Adults, elderly patients:

    Ointment is applied to the affected surface 2-4 times a day.

    With internal hemorrhoids, a small amount of ointment (the size of a pea) is introduced into the rectum 2-4 times a day.

    With a decrease in symptoms, the drug can be used less often.

    The course of treatment is 5-7 days.

    Children:

    Children under 12 months of ointment can not be used.

    When using the drug in children, it should be avoided for a long time and on a vast surface regardless of age.

    Side effects:

    The use of local glucocorticosteroids can primarily cause local side effects: deterioration of wound healing, burning sensation, itching, irritation, dryness, thinning of the skin, increased sensitivity of the skin.

    With prolonged use of glucocorticosteroids - skin atrophy, local hirsutism, telangiectasia, purpura, hypopigmentation, hypertrichosis, folliculitis, acne vulgaris, fungal infection, allergic contact dermatitis, diaper rash.

    When applied to large surfaces - systemic manifestations of side effects of glucocorticosteroid (growth retardation, Itenko-Cushing syndrome, benign increase in intracranial pressure after treatment, hyperglycemia, glucosuria, hypokalemia, increased blood pressure)

    With prolonged use and on a large surface due to the systemic action of lidocaine, bradycardia may occur.

    Overdose:

    Acute overdose is unlikely, however, in case of chronic overdose or improper use of the drug, symptoms may occur due to the systemic action of the glucocorticoid, and bradycardia with excessive administration of the drug into the rectum (due to lidocaine), it is necessary to stop treatment or gradually reduce the dose.

    Interaction:

    When the drug is used locally, drug interactions are not known.

    Special instructions:

    If possible, avoid prolonged therapy, especially in children, because of the possible suppression of adrenal function. The drug in children can be used with caution, in a minimal dose, ensuring the achievement of therapeutic effect. The duration of therapy in children should not exceed 5 days.

    Avoid accidental contact with the eye or periorbital area. In case of contact, flush with water.

    The development or spread of secondary infection requires the withdrawal of the drug and the appointment of antimicrobial or antifungal therapy.Bacterial infection is maintained in warm, moist conditions, so the skin should be cleansed before each application of the ointment.

    Application on a large surface or use for a long time can lead to systemic absorption of active components.

    With prolonged use of the drug in one area, it can cause skin atrophy, especially in young people.

    Effect on the ability to drive transp. cf. and fur:

    There is no data on the effect of Aurobin® on the ability to drive a vehicle or to work in conditions of increased attention.

    Form release / dosage:

    Ointment for rectal and external use.

    Packaging:

    For 20 g of the drug in an aluminum tube.

    1 tube with instructions for use in cardboard pack.

    Storage conditions:

    At a temperature of 8 to 15 ° C.

    Inaccessible to children!

    Shelf life:

    2 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:On prescription
    Registration number:П N014951 / 01
    Date of registration:09.10.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:GEDEON RICHTER, OJSC GEDEON RICHTER, OJSC Hungary
    Manufacturer: & nbsp
    Representation: & nbspGEDEON RICHTER OJSC GEDEON RICHTER OJSC Hungary
    Information update date: & nbsp04.10.2017
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