Included in the formulation
АТХ:V.03.A Other different drugs
Pharmacodynamics:Bacteriophage dysentery polyvalent causes a specific lysis of Shigella Flexner and Sonne - the causative agents of shigellosis.
Pharmacokinetics:Not described.
Indications:Treatment and prevention of bacterial dysentery caused by Shigella flexneri serovars 1, 2, 3, 4, 6 and Shigella sonnei.
I.A00-A09.A03.0 Shigellosis caused by Shigella dysenteriae
Contraindications:Individual intolerance; children under 1 year.
Carefully:Bacteriophage dysentery polyvalent should be used with caution in severe forms of shigellosis with severe intoxication phenomena, in connection with the possibility of strengthening the latter in mass lysis of shigella as well as in the use of antibiotics of bactericidal action.
Pregnancy and lactation:Action category for the fetus by Food and Drug Administration (US Food and Drug Administration) - not determined.
The use of this medication during pregnancy and during breast-feeding is possible in the presence of infections caused by phagosensitive strains of bacteria (on the recommendation of a doctor).
Adequate and well-controlled studies on humans and animals have not been conducted.There is no information on the penetration into breast milk.
Dosing and Administration:Treatment and prevention of bacterial dysentery in adults and children one year.
The drug is intended for oral administration. To treat the drug take 3 times a day for 1 hour before meals from the first day of the disease for 7-10 days.
Recommended dosage of the drug
| Age | Dose for 1 reception |
| from 1 year to 3 years | 1 tablet |
| from 3 years to 8 years | 1-2 tablets |
| from 8 years and older | 2-3 tablets |
In dysentery, characterized by a weakly expressed colitis syndrome, and during the reconvalescence, a combination of a double intake of tablets with a single rectal administration of a single age-related dose of a liquid bacteriophage (bacteriophage dysentery polyvalent, solution for ingestion and rectal administration) is recommended in accordance with the instruction for its use in the form of an enema after evacuation of the intestine.
As a preventive measure the drug recommended for use during the group of diseases in organized groups and families. Optimal schemes of use - a daily intake of a single age dose. The duration of the drug is determined by the conditions of the epidemiologicalof the situation.
Side effects:Allergic reactions, indigestion.
Interaction:The use of the drug is possible in combination with other drugs, including antibiotics.
Special instructions:Important conditions for effective phage therapy are preliminary determination of phagosensitivity and early application of the drug.
Before use, the vial with a liquid bacteriophage must be shaken.