Barboval® (Barbovalum®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Similar drugsTo uncover
Dosage form: & nbspdrops for ingestion
Composition:1 ml of the preparation contains:

active substances: etylbromisovalerianate - 18 mg in terms of 100% substance, levomenthol solution in mentilizovalerate - 80 mg; phenobarbital - 17 mg;

Excipients: Sodium acetate trihydrate - 1 mg, rectified ethyl alcohol (ethanol) - 0.73 ml of purified water to 1 ml.

Description:Transparent colorless liquid with a specific aromatic odor.
Pharmacotherapeutic group:Coronarodilating agent of reflex action
ATX: & nbsp
  • Other combination drugs for the treatment of heart disease
    • Pharmacodynamics:

    Barboval ® - a combined drug, the therapeutic effect of which is due to the pharmacological properties of the components that make up its composition.

    Ethyl ether α-bromoisovaleric acid It has reflex, sedative and spasmolytic effect due to stimulation advantageously receptors oral cavity and nasopharynx, reduction of the reflex excitability in the central parts of the nervous system and increased braking processes in neurons of the cortex and subcortical brain structures and decreased activity of central vasomotor centers and local direct spasmolytic action on smooth muscles.

    Phenobarbital strengthens the sedative effect of other components of the drug, helps reduce excitation of the central nervous system and facilitates the onset of sleep. Barboval® reduces the stimulating effects on vasomotor centers, coronary and peripheral vessels, reducing blood pressure, eliminating and preventing spasms of blood vessels, especially cardiac vessels.

    Levomentola the solution in mentilizovalerate has a sedative effect, has a moderate reflex vasodilator action due to irritation of sensitive nerve endings, slows the peristalsis of the gastrointestinal tract ..

    Indications:Barboval® is used as a symptomatic (sedative and suasodilating) remedy for functional disorders of the cardiovascular system (including tachycardia), disturbed sleep, neurosis-like conditions, accompanied by increased irritability, a state of excitation with pronounced vegetative manifestations. As an antispasmodic agent of intestinal ghosts.
    Contraindications:

    Hypersensitivity to any of the components of the drug, severe hepatic and / or renal failure, alcoholism, craniocerebral trauma or disease brain, pregnancy, lactation, age under 18 years (effectiveness and safety not established).

    Pregnancy and lactation:

    The drug is not prescribed for pregnant women and women breastfeeding.

    Dosing and Administration:Is taken orally, with a small amount (30-50 ml) of water or a piece of sugar under the tongue. Doses of the drug are set individually. For 10-15 drops at the reception, 2-3 times a day, 20-30 minutes before meals. The duration of the course of treatment is determined by the doctor. After a break of 10-15 days, the course of treatment can be repeated.
    Side effects:

    Drowsiness, nausea, dizziness, lacrimation, slowing of the heart rate, decreased concentration, skin rash, hives, itching. These phenomena occur when the dose is reduced or the drug is withdrawn. Very rarely possible allergic reactions. With prolonged use, there may be a dependence on the drug and bromism.

    Overdose:

    With prolonged or frequent use, cumulation of the drug may occur, which leads to clinical manifestations of an overdose, namely:

    • oppression of the central nervous system;
    • nystagmus, ataxia, lowering blood pressure.

    Manifestations of chronic bromide poisoning are: depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, movement coordination disorders.

    Permanent long-term use of the drug may cause addiction, drug dependence, withdrawal symptoms, and a sudden discontinuation of the use of the "withdrawal" syndrome. Long-term use of the drug is sometimes accompanied by increased psychodynamic activity instead of the expected sedation.

    Treatment is symptomatic.

    Interaction:Simultaneous use with neuroleptics and tranquilizers potentiates, but with stimulants of the central nervous system - weakens the effect of each component of the drug. Barboval®, containing in its composition derivatives of barbituric acid, enhances the action of local anesthetic, analgesics and hypnotics. Ethanol enhances the effects of the drug and can increase its toxicity. The presence of phenobarbital in the composition of Barboval® can induce liver enzymes, and this makes it undesirable to use it simultaneously with drugs that are metabolized in the liver (with coumarin derivatives,griseofulvin, glucocorticoids, oral contraceptives), because their effectiveness will decrease as a result of a higher metabolic rate. The drug increases the toxicity of methotrexate.
    Special instructions:

    Children. Experience in the use of the drug for the treatment of children there, so it is not used in pediatric practice.

    Effect on the ability to drive transp. cf. and fur:The preparation contains 62% by volume of ethanol and phenobarbital, which can cause a disruption in the coordination and speed of psychomotor reactions, so when taking the drug should be careful to persons working with mechanisms, drivers of vehicles, etc.
    Form release / dosage:Drops for ingestion.
    Packaging:

    To 25 ml in bottles of dark glass, ukuporennyh stoppers, droppers and caps screwed or lids of the closure-screwed with the control of the first autopsy. Each bottle, along with instructions for medical use, is placed in a pack of cardboard.

    Storage conditions:

    Store in a dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date shelf life.

    Terms of leave from pharmacies:Without recipe
    Registration number:П N015255 / 01
    Date of registration:19.05.2008 / 10.07.2014
    Expiration Date:Unlimited
    The owner of the registration certificate:FARMAK, PAO FARMAK, PAO Ukraine
    Manufacturer: & nbsp
    Information update date: & nbsp21.01.2017
    Illustrated instructions
      Instructions
      Up