Belogen ® - anti-inflammatory, anti-allergic, antipruritic, antibacterial.
Betamethasone dipropionate - synthetic glucocorticosteroid (GCS), anti-inflammatory, antiallergic, antipruritic and vasoconstrictive action. When applied to the skin surface, it narrows the vessels, relieves itching, reduces the release of inflammatory mediators (from eosinophils and mast cells), interleukins 1 and 2, interferon gamma (from lymphocytes and macrophages), inhibits the activity of hyaluronidase and reduces the permeability of the vascular wall.
Interacts with specific receptors in the cytoplasm of the cell, stimulates the synthesis of mRNA, inducing the formation of proteins, including lipocortin, mediating cellular effects.
Lipocortin depresses phospholipase A2, blocks the release of arachidonic acid and the biosynthesis of endoperoxides, prostaglandins, leukotrienes (contributing to the development of inflammation, allergy and other pathological processes).
Gentamicin is an antibiotic with a broad spectrum of action of the aminoglycoside group. It has bactericidal action and provides highly effective local treatment of primary and secondary bacterial skin infections. Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumonia; and Gram-positive bacteria: Streptococcus spp. (sensitive strains of β- and α-hemolytic streptococcus groups A), Staphylococcus aureus (coagulase-positive, coagulase-negative strains and some strains producing penicillinase).