Benoxi - instructions for use, dose, side effects, contraindications

Active substanceOxibuprocaineOxibuprocaine

Similar drugsTo uncover

Benoxi

drops d / eye

Unimed Pharma s.r.o. The Slovak Republic

Inokain®

drops d / eye

Sentiss Pharma Pvt. Ltd. India

Dosage form: & nbspeye drops

Composition:

10 ml of solution contains:

active substance: hydroxybuproquin hydrochloride 40 mg;

Excipients: boric acid 200 mg, chlorhexidine diacetate 1 mg, water purified to 10 ml.

Description:

A clear, colorless solution.

Pharmacotherapeutic group:Local anesthetic

ATX: & nbsp

S.01.H.A Local Anesthetics

S.01.H.A.02 Oxibuprocaine

Pharmacodynamics:

Has a local anesthetic effect of short action, reversibly blocks sensitive nerve endings and conductors; penetrates the membrane of nerve cells, disrupts the transmembrane transport of ions (especially sodium), reduces the flow of pulses in the central nervous system, does not affect the size of the pupil of the eye and its ability to accommodation. Easily absorbed through the mucous membranes.

Superficial anesthesia of the conjunctiva and the cornea after the application of eye drops occurs 1-3 minutes and lasts 10-20 minutes.

Indications:

Superficial anesthesia of the cornea and conjunctiva with small surgical interventions (for example, to remove superficial and deeply located foreign bodies), with tonometry, gonioscopy or other diagnostic examinations; before subconjunctival and retrobulbar injections.

Contraindications:

Hypersensitivity to the components (including other local anesthetics of the group of esters of para-aminobenzoic acid or amides), children's age (up to 2 years).

Pregnancy and lactation:

Clinical experience in the use of the drug during pregnancy and during lactation is not enough. The use of Benoxi in pregnancy and during breastfeeding is possible only in cases where the expected benefit of therapy for the mother exceeds the potential risk to the fetus or infant.

Dosing and Administration:

Locally. In the interval between individual injections of the drug, the eyes should be closed.

Anaesthesia of the cornea and conjunctiva

To remove foreign bodies located on the surface: in the conjunctival sac 1 drop 3 times for 5 minutes.

To remove deeply located foreign bodies: 1 drop 5-10 times with an interval of 30-60 seconds.

Before subconjunctival and retrobulbar injection: 1 drop 3 times for 5 minutes.

For tonometry, gonioscopy and other examinations: 1-2 drops.

Side effects:

Maybe: short-term sensation of tingling, burning and congestion hyperemia; damage to the corneal layer of the epithelium, infiltration of the corneal stroma; allergic reactions in the eyelashes and conjunctiva.

Rarely: keratitis and erosion of the surface of the cornea.

Overdose:

Symptoms: irritation, insomnia, nausea, vomiting, convulsions; impaired breathing, coma, hypotension, cardiac arrest.

Treatment: symptomatic.

Interaction:

The drug enhances the effect of succinylcholine and sympathomimetics and reduces the effects of sulfonamides and beta-blockers.

The preparation of Benoxi includes a preservative chlorhexidine diacetate, which is incompatible with the solution of fluorescein (with the simultaneous use of precipitate). Also, the drug is incompatible with silver nitrate, with substances of an alkaline nature and mercury salts.

Special instructions:

The drug is intended only for instillations in the conjunctival sac. Do not use for injection.

It is not intended for long-term therapy in the complex treatment of eye diseases. Long-term, repeated and long-term use (as well as other localanesthetics), can lead to a stable clouding of the cornea.

Effect on the ability to drive transp. cf. and fur:

After applying Benoxi's drug to drive vehicles and perform work that requires a high rate of psychomotor reactions, it is allowed not earlier than one hour later.

Form release / dosage:Eye drops, 4 mg / ml.

Packaging:

Plastic bottle-dropper for 10 ml with a screwed plastic stopper in a cardboard pack together with instructions for use.

Storage conditions:

In dry, the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date printed on the package.

The bottle after opening is usable for 14 days. After instillation, the vial must be closed immediately and tightly.

Terms of leave from pharmacies:On prescription

Registration number:П N016007 / 01

Date of registration:02.12.2009 / 21.10.2011

Expiration Date:Unlimited

The owner of the registration certificate:Unimed Pharma s.r.o.Unimed Pharma s.r.o. The Slovak Republic

Manufacturer: & nbsp

UNIMED PHARMA, s.r.o. The Slovak Republic

Representation: & nbspUNIMED PHARMA SROUNIMED PHARMA SRORussia

Information update date: & nbsp23.01.2017

Illustrated instructions

Instructions

Benoxi (Benoxi)