Dalargin (Dalargin)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspsolution for intravenous and intramuscular administration
Composition:Aactive substance:

Dalargin (Tyrosyl-D-alaiyl-glinyl-phenylalanyl-leucyl-arginine diacetate [based on tyrosyl-D-alanyl-glycyl-phenylalanyl-leucyl-arginine]) - 1 mg

Excipients:

Sodium chloride 9 mg

Water for injection - up to 1 ml

1 M acetic acid solution to pH 5.0-7.0

Description:

Transparent colorless liquid. The smell of acetic acid is allowed.

Pharmacotherapeutic group:Antiulcer
ATX: & nbsp
  • Other antiulcer drugs
    • Pharmacodynamics:
    Synthetic hexapeptide, analogue of leucine-enkephalin. Suppresses proteolysis and promotes the healing of stomach and duodenal ulcers. Has a moderate antisecretory activity, reduces the acidity of gastric juice.
    Suppresses the external secretion of the pancreas in response to various stimuli (food, secretin, etc.). When the pancreas is damaged in the experiment, it is shown that the drug reduces hyperfermentation, limits foci of necrosis and promotes their replacement with a full tissue, weakens the synthesis of proteolytic enzymes by the pancreas.
    Has a slight hypotensive effect.
    Indications:
    Stomach ulcer and duodenal ulcer in the acute phase, acute pancreatitis, acute necrotic pancreatitis.
    Contraindications:
    Hypersensitivity, arterial hypotension, acute infectious processes, pregnancy.
    Dosing and Administration:
    The drug is administered intramuscularly or intravenously.
    With exacerbations of peptic ulcer of the stomach and duodenum, a single dose of 1-2 mg, the highest daily - 5 mg. The course of treatment is 3-4 weeks. The total dose for the course of treatment is 30-50 mg.
    In acute pancreatitis, the drug is administered intravenously at a dose of 2 mg, then 5 mg 1-2 times a day. The course of treatment 4-6 days.
    When pancreatic necrosis is administered intravenously 5 mg 3-4 times a day (after 6-8 hours). The course of treatment is from 2 to 6 days.
    Side effects:
    Allergic reactions, lowering blood pressure.
    Special instructions:
    The safety of the drug in children and during breastfeeding is not established.
    Form release / dosage:RAsterol for intravenous and intramuscular injection 1 mg / ml.
    Packaging:

    Solution for intravenous and intramuscular injection 1 mg / ml in ampoules of 1 ml.

    5 ampoules in the outline of the cell.2 contour squares with instructions for use, ampoule scarifier in a pack of cardboard.

    For 10 ampoules with instructions for use, ampoule in a pack orbox of cardboard.

    When packaging ampoules that have a ring ofscrap or point for dissection, the ampoule scaper does not invest.

    5 ampoules in a cassette outline package. 2 cassette contour packs with instructions for use in a pack of cardboard.

    Storage conditions:

    In the dark place at a pacefrom 4 to 8 ° C.

    Keep out of the reach of children.

    Shelf life:
    3 years. Do not use after the expiry date printed on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:LS-000652
    Expiration Date:Unlimited
    The owner of the registration certificate:MICROGEN FGUP Scientific and Production Association MICROGEN FGUP Scientific and Production Association Russia
    Manufacturer: & nbsp
    Representation: & nbspMICROGEN FGUP Scientific and Production Association MICROGEN FGUP Scientific and Production Association Russia
    Information update date: & nbsp17.03.2017
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