Bien - a mixture of ethyl esters of polyunsaturated fatty acids, obtained from the lipids of the mycelial fungus Entomophthora virulenta, family Entomophthoraceae, grade Zygomycetes, strain "E.Imi", stabilized by alpha-tocopherol acetate (vitamin E). Bien for 90-95% consists of higher fatty acids. Biene contains: ethyl esters of α-linolenic acid (Ѡ-3); linoleic acid (Ѡ-6); γ-linolenic acid (Ѡ-6); arachidonic acid (Ѡ-6); eikosadienoic acid (Ѡ-6); eicosatrienoic acid (co-6); palmitic acid (co-7); palmitoleic acid (Ѡ-9); oleic acid (Ѡ-9), as well as ethyl esters of stearic acid and myristic acid. Unlike unsaturated fatty acids, including essential (linoleic,α-linolenic and arachidonic) are important components of biomembranes and sources of eicosanoids - universal bioregulators for the functional activity of cells and tissues. Biene is characterized by a balanced ratio polyunsaturated fatty acids of families Ѡ-6 and Ѡ-3 series, has a cytoprotective effect, enhances reparative processes.
Essential polyunsaturated fatty acids (PUFA) and their derivatives - eicosanoids - have a modulating effect on the development of hyperreactivity and the formation of allergic inflammation, proliferative processes. Metabolite of arachidonic acid prostaglandin PGE2 at low concentrations inhibits the migration of leukocytes and the release of inflammatory mediators from mast cells. Eicosanoids, which exert a dose-dependent anti-inflammatory effect, also include PGE1 PGE2a, NGD2.
Ointment has an anti-inflammatory effect and stimulates reparative processes in the skin (reduces flushing and swelling, reduces the burning sensation of the skin, contributes to the epithelization of the wound defect).