Dioxydin is prescribed in a hospital. Apply externally, intracavitary.
1% dioxygen solution can not be used for intravenous administration, because of instability of the solution when stored at low temperatures.
External application. Apply 0.1% - 1% solutions of dioxidine. To obtain 0.1-0.2% solutions, ampoule drug solutions are diluted to the desired concentration with sterile isotonic sodium chloride solution or water for injection. For the treatment of superficial infected purulent wounds, wipes moistened with 0.5-1% dioxygen solution are applied to the wound. Deep wounds after treatment, loose plugging with swabs moistened with 1% dioxygen solution, and in the presence of a drainage tube, 20 to 100 ml of a 0.5% solution of the drug is injected into the cavity.
For the treatment of deep purulent wounds in osteomyelitis (bruises of the hand, feet) 0.5-1% solution of the drug in the form of trays or special treatment of the wound with a solution of the drug for 15-20 minutes (introduction of the solution into the wound for this period) with subsequent application dressings with 1% solution of dioxidine.
Dioxydin in the form of 0.1-0.5% solutions can be used to prevent infection after surgery. According to the indications (patients with osteomyelitis) and with good tolerability treatment can be carried out daily for 1.5-2 months.
Intracavitary injection. Depending on the size of the purulent cavity, 10 to 50 ml of a 1% solution of dioxidine are administered per day. Dioksidina solution is injected into the cavity through a catheter, drainage tube or syringe.
The maximum daily dose for administration in a cavity of 70 ml of a 1% solution.
The drug is injected into the cavity usually once a day. According to the indications, it is possible to administer a daily dose in two divided doses. With good tolerability and the presence of indications, the drug can be administered daily for 3 weeks or more. If necessary, repeat courses are conducted after 1-1.5 months.