Included in the formulation
АТХ:D.06.C Antibiotics in combination with other antimicrobials
Pharmacodynamics:Combined drug, antimicrobial, anti-inflammatory, analgesic and necrolytic.
The drug is active against gram-positive and gram-negative microorganisms, as well as anaerobes.
Pharmacokinetics:The ointment easily penetrates deep into the tissues, transporting the levomycetin bound to polyethylene glycol and sulfadimethoxin. Due to the high hydration activity, the drug in a short time (2-3 days) usually provides the elimination of perifocal edema and purification of the wound from purulent necrotic contents. Methyluracil, which is part of the drug, accelerates the healing of wounds, stimulates cellular defense factors. Trimecaine is a local anesthetic, it acts more strongly and more prolonged than procaine (novocain), low toxicity, does not have an irritant effect.The drug does not have the ability to cumulate and has no locally irritating properties.
Indications:Purulent wounds (including those infected with mixed microflora: burns, hard-healing ulcers) in the first (purulent-necrotic) phase of the wound process.
XIX.T08-T14.T14.1 Open wound of unspecified area of the body
Contraindications:Hypersensitivity to the components of the drug.
Carefully:During pregnancy and lactation - strictly according to the doctor's prescription.
Pregnancy and lactation:Clinical experience of using the drug in pregnant and lactating women is limited, so the ointment should be used according to the doctor's indications, when the intended benefit for the mother will exceed the potential risk for the fetus and the baby.
Dosing and Administration:Locally, externally. Impregnated with ointment, sterile gauze napkins are applied to the affected parts of the body or through a catheter (drainage tube) into the cavity of the purulent process, pre-warmed to 35-36 ° C ointment, daily, until the wound is completely cleansed.
Side effects:Possible local allergic reactions (skin rash).
Overdose:External preparation. Overdose is unlikely.In case of an overdose, cancel therapy and perform symptomatic treatment.
Interaction:Do not use simultaneously with other external agents to avoid cross-reactive negative reactions.
Special instructions:Before applying the dressing, it is necessary to treat the wound (removal of necrotic tissues and washing with hydrogen peroxide solution).