Included in the formulation
АТХ:A.05.A.X Other drugs for the treatment of bile duct diseases
Pharmacodynamics:Action choleretic, choleretic.
Excites receptors of the intestinal mucosa and reflexively stimulates hepatic secretion. Increases the amount of bile, the content of cholesterol and bile acids in it, the osmotic gradient between bile and blood, strengthens the osmotic filtration of water and electrolytes into the bile capillaries. Increases the flow of bile through the bile ducts, inhibits the formation of bile and cholesterol stones, strengthens the secretory and motor functions of the digestive tract.
Increasing the secretion of bile acids activates the lipase of the pancreatic juice and improves the emulsification of fats with the subsequent normalization of their assimilation. Increases the level of secretin in the blood, the content of bicarbonates and the volume of secreted pancreatic juice. Strengthens the secretory function of the stomach.
Pharmacokinetics:The maximum effect develops 15 minutes after ingestion.
Indications:Dyspepsia caused by a violation of the formation and secretion of bile in chronic cholecystopathies, chronic hepatopathies and chronic pancreatitis.
XI.K20-K31.K30 Dyspepsia
XI.K70-K77.K73.2 Chronic active hepatitis, not elsewhere classified
XI.K80-K87.K81 Cholecystitis
XI.K80-K87.K86.1 Other chronic pancreatitis
XI.K80-K87.K83.1 Blockage of the bile duct
Contraindications:Hypersensitivityacute hepatitis with complete and incomplete obstruction of the biliary tract, acute cholecystitis, acute cholangitis, acute pancreatitis, empyema of the gallbladder
Carefully:Pregnancy, children's age.
Pregnancy and lactation:Category FDA is not defined. Adequate and well-controlled clinical studies of the safety of the use of phenypentol have not been conducted. If you need to use it in pregnancy, you should evaluate the expected benefit of therapy for the mother and the potential risk to the fetus.
Dosing and Administration:Take inside 200 mg 3 times / day immediately before eating, squeezed with enough water (at least 200 ml). The course of treatment is long.
Side effects:Sensation of bursting (overflow and pressure) in the epigastric region, heartburn, nausea, flatulence.
Special instructions:Use with caution in pediatrics. Currently, there is insufficient clinical experience with the use of phenypentol in children.