Fenistil® Pencivir (Fenistil® Pencivir)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substancePenciclovirPenciclovir
Dosage form: & nbsp

cream for external use, cream for external use (with toning effect).

Composition:

1 g of cream contains:

Active substance - 10 mg of penciclovir.

Cream for external use:

Excipients: cetomacrogol 1000 9.40 mg, cetostearyl alcohol

77.20 mg, paraffin soft white 148,50 mg, paraffin liquid 59.40 mg, propylene-

glycol 416.80 mg, purified water 278.70 mg.

Cream for external use (with toning effect): Excipients: cetomacrogol 1000 9.40 mg, cetostearyl alcohol 77.20 mg, paraffin soft white 148,50 mg, paraffin liquid 59.40 mg, propylene glycol 415.55 mg, purified water 277.45 mg, iron dye oxide red 1.70 mg, iron oxide dye yellow 0.80 mg.

Description:

a homogeneous cream of white color.

Pharmacotherapeutic group:antiviral for topical use.
ATX: & nbsp

D.06.B.B.06   Penciclovir

Pharmacodynamics:

Cream Fenistil® Pencivir is designed to treat cold sores ("colds") on the lips (Herpes labialis). Penciclovir is an active component that is an antiviral agent with respect to viruses Herpes simplex 1 and 2 type, virus Varicella zoster.

The virus can be inactive in the body for a long time period of time.At the time of activation (for example, due to fatigue, colds, flu), the virus begins to multiply, which leads to the development of a "fever" in the form of bubble rashes, etc., especially often on the lips or in areas around them.

Penciclovir blocks the virus and stops its reproduction. The use of the drug leads to a faster recovery, a decrease in the intensity of pain, the period of risk of transmission of a viral infection is reduced.

Pharmacokinetics:

With external application, the preparation is practically not subjected to systemic absorption. Modern analytical methods can not be identified penciclovir in the blood or urine of healthy volunteers after applying Fenistil® Pencivir cream in concentrations many times higher than therapeutic.

Penetrating into the cells affected by the virus, penciclovir quickly passes into penciclovir triphosphate, which has pharmacological activity and persists in the affected cells for 12 hours.

Indications:Recurrent herpes simplex {Herpes labial is) with localization on the lips.
Contraindications:

Hypersensitivity to penciclovir, famciclovir or to any of the inactive ingredients,included in the preparation. Children under 12 years.

Carefully:Pregnancy, the period of breastfeeding.
Pregnancy and lactation:

Application during pregnancy and during breastfeeding is possible according to the doctor's indication, when the expected benefit for the mother exceeds the possible risk for the fetus and the baby.

Dosing and Administration:

Outwardly. Adults and children from 12 years.

A small amount of cream is squeezed out tip of the finger and apply to the affected site every 2 hours (approximately 8 times in day). The cream can also be applied with help a cotton swab or disposable applicator (for packages, containing applicators). Course of therapy spend for 4 days.

Cream for external use (with toning effect): cream with toning effect has masking properties, it masks the areas affected by herpes on the lips and on the skin around the mouth.

Side effects:

Burning, tingling or numbness in the place of application.

Overdose:No cases of drug overdose have been reported.
Interaction:Any drug interactions for the cream Fenistil® Pencivir are not known.
Special instructions:

Wash hands thoroughly before and after applying the cream.Treatment should be started as early as possible, with the first signs of infection. However, even with the development of herpes in the bubble stage, the use of the cream Fenistil® Pencivir reduces the healing time (heals the affected areas, reduces pain and shortens the duration of peeling of the crust, formed from the viral effect).

Consult your physician before using Fenistil® Pencivir Cream if the patient has a weakened immune system or is not sure that he develops herpes.

The drug should be used only on areas affected by herpes on the lips and on the skin around the mouth. It is not recommended to apply the cream to the mucous membrane of the mouth, nose, or in the eyes and genital area.

It is necessary to conduct a full course of therapy with Fenistil® Pencivir cream for 4 days in order to achieve the greatest effect from the therapy, even if the signs of infection disappear after one to two days of treatment.

It is necessary to consult a doctor if the condition worsens or if there is no improvement after 4 days of therapy.

Effect on the ability to drive transp. cf. and fur:Does not affect.
Form release / dosage:

Cream for external use 1%.

By 2 g or 5 g of the drug in aluminum a tube with a screw cap. Tuba

together with instructions for use placed in a cardboard box.

For Fenistil® Pencivir, a cream for external application 1% addition: By 2 g or 5 g of the drug in aluminum tube with a screw cap. The tube together with the instruction for use is placed in a plastic case with a mirror, two plastic bags containing 10 disposable plastic applicators, and instructions for use. The pencil case has a label with the control of the first autopsy.

Packaging:cream for external use 1%, cream for external use (with toning effect) 1% (tuba) 2/5 g х 1 (carton pack); [cream for external use 1% (tube) 2/5 g x 1 + sachet (10 disposable applicators) x 2] x 1 (pencil case with a mirror)
Storage conditions:

At a temperature not higher than 30 ° C, do not freeze. Keep out of the reach of children.

Shelf life:3 years. Do not use after the expiration date.
Terms of leave from pharmacies:On prescription
Registration number:No. ЛС-001926
Date of registration:19.08.2011
The owner of the registration certificate:Новартис Консьюмер Хелс САНовартис Консьюмер Хелс СА Switzerland
Manufacturer: & nbsp
Representation: & nbspNOVARTIS CONSUMER HELS S.A. (part of Novartis groups) NOVARTIS CONSUMER HELS S.A. (part of Novartis groups) Switzerland
Information update date: & nbsp26.08.2015
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