Similar drugsTo uncover Dosage form: & nbspgel for external use Composition:1 g of gel contains:Active substances: terbinafine hydrochloride (in terms of 100% substance) 0.01 g, urea-0.10 g;Excipients: Butylhydroxytoluene (dibunol), carbomer (carbopol), trolamine triethanolamine thermostable, 2,2I,2II - nitriloethanol), propylene glycol - up to 1 g. Description:Colorless transparent or translucent gel with a subtle smell. Pharmacotherapeutic group:Antifungal agent ATX: & nbspAntifungal preparations for topical use others in combination Pharmacodynamics:Antifungal drug for external use. Terbinafine - active substance of the preparation Fungoterbin NEO, is an allylamine and has a wide spectrum of antifungal action.Terbinafine disrupts the biosynthesis of ergosterol in the fungi in the early stages. This leads to a deficit of ergosterol and to intracellular accumulation of squalene, which causes death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus. This enzyme does not belong to the cytochrome P450 system, therefore terbinafine does not affect the metabolism of hormones or other medications.Terbinafine has a fungicidal effect against dermatophytes, molds and some dimorphic fungi. Activity with respect to yeast-like fungi, depending on their type, may be fungicidal or fungistatic.Urea is the second active ingredient of Fungoterbin NEO, has a softening, exfoliating and moisturizing effect, it can increase dermatopenrint (penetration into the skin) and create high concentrations of terbinafine in the skin. Urea promotes water binding and softening of the stratum corneum. Pharmacokinetics:With topical application of the gel, less than 5% of terbinafine is absorbed, so the systemic effect of the drug is minimal. The drug quickly penetrates the skin and accumulates in the sebaceous glands. Indications:Treatment and prevention of fungal diseases:Fungal skin infections caused by dermatophytes, such as Trychophyton (eg, j T. rubrum, T.mentagrophytes, T.verrucosum, T. violaceum), Microsporum canis and Epidermophyton floccosum.Skin infections caused by yeast-like fungi of the genus Candida (eg, Candida albicans).Multicolored lichen (Pityrosporum versicolor), caused by Pityrosporum orbiculare (also known as Malassezia furfur). Contraindications:Hypersensitivity to the components of the drug, children's age (up to 2 years). Carefully:Hepatic and / or renal failure, alcoholism, blood diseases, tumors, metabolic diseases, pathology of the vessels of the limbs, pregnancy, lactation. Pregnancy and lactation:In experimental studies teratogenic properties of terbinafine were not revealed. The use of the drug during pregnancy is possible in cases where the potential benefit to the mother exceeds the risk to the fetus. Dosing and Administration:Outwardly. The drug is applied to the skin once or twice a day. Gel put a thin layer on the affected skin and lightly rub. To improve the effectiveness of treatment, it is possible to use occlusive dressings. In infections accompanied by intertrigo (under the mammary glands, in the interdigital spaces, between the buttocks, in the groin area), the places of applying the gel can be covered with gauze, especially at night. Average duration and frequency of treatment:Dermatomycosis of trunk, drumsticks: 1 week 1 time per day.Dermatomycosis of the feet: 1 week 1 time per day.Candidiasis of the skin: 1-2 weeks 1 or 2 times a day.Multicolored lichen: 1 week 1 or 2 times a day. Side effects:In rare cases, redness of the skin, itching or burning sensation may occur at the site of application of the gel, however, these phenomena rarely led to the need to stop treatment.The above symptoms should be distinguished from allergic reactions, for example, urticaria, which occur rarely, however, when they appear, you must stop treatment. Overdose:No cases of drug overdose have been reported. If the drug is accidentally ingested, the same side effects can be expected, as with an overdose of Fungoterbin® tablets: nausea, anorexia, upper abdominal pain, diarrhea. Interaction:Any drug interactions with terbinafine are not known externally. Special instructions:Reducing the severity of clinical manifestations is usually noted in the first days of treatment.In the case of irregular treatment or premature termination, there is a risk of renewal of the infection. In the event that after two weeks of treatment there are no signs of improvement, the diagnosis should be verified.The gel is intended for external use only. Avoid contact with eyes and mucous membranes. the preparation may cause irritation. In case of accidental ingestion of the drug into the eyes, they should be washed immediately with running water,and in case of development of persistent phenomena of irritation it is necessary to consult a doctor. Form release / dosage:Gel for external use. Packaging:By 10, 15, 20, 25, 30, 40, 50 or 100 g in aluminum tubes or in polyethylene laminated tubes. Each tube together with instructions for medical use of the drug is placed in a pack of cardboard. Storage conditions:Store at a temperature not exceeding 20 ° C.Keep out of the reach of children. Shelf life:2 years. Do not use the drug after the expiry date printed on the package. Terms of leave from pharmacies:Without recipe Registration number:LSR-004847/10 Date of registration:27.05.2010 The owner of the registration certificate:NIZHFARM, JSC NIZHFARM, JSC Russia Manufacturer: & nbspNIZHFARM, JSC Russia Information update date: & nbsp2016-01-31 Illustrated instructions × Illustrated instructions Instructions