Significant interactions of Hexabrix 320 with other drugs have not been identified, however,this medication should not be confused with others when administered.
Combinations of drugs that require precaution:
Beta-blockers:
In the case of development of shock or lowering of arterial pressure with the administration of yoxagolic acid, beta-adrenoblockers suppress compensatory reactions from the side of the cardiovascular system.
Before the X-ray examination, the use of beta-blockers should be stopped, if possible. If continuity of therapy is extremely important for the patient, you should have appropriate resuscitation equipment at hand.
Diuretics:
If diuretics caused dehydration, this increases the risk of developing acute renal failure, especially when using large doses of yogic acid. Before administering yoxagolic acid, the patient should be rehydrated.
Metformin:
In patients with diabetes mellitus, a decrease in renal function caused by an X-ray examination may be a trigger factor in the development of lactic acidosis. Metformin should be temporarily discontinued 48 hours before and resumed only 2 days after the X-ray examination.
Combinations of drugs that should be taken into account:
Interleukin II:
The risk of developing a reaction to the administration of contrast agents is increased if the patient previously received intravenous therapy with interleukin II: skin rash or, less often, lower blood pressure, oliguria and even kidney failure.