Combination drug for external use.
Hydrocortisone
By inhibition of phospholipase A activity2 and reducing the release of arachidonic acid from the phospholipids of cell membranes reduces the production of leukotrienes and prostaglandins. Due to this suppresses the development of inflammatory manifestations: pain, swelling, fever and redness in the area of inflammation. It inhibits the expression of the cyclooxygenase-2 gene, which also leads to inhibition of prostaglandin synthesis.
Reduces the main substance of the connective tissue, weakening the exudative and proliferative processes in the skin. Inhibits cellular kinins, which have proteolytic activity. Prevents the access of macrophages and T-sensitized lymphocytes to the foci of inflammation.
It has anti-inflammatory, anti-edematous and anti-allergic effect.
Chlorhexidine
Nonspecifically binds to phospholipids of the bacterial cell wall, inactivates ATPase and dehydrogenase, breaks the permeability of the membrane for potassium, amino acids and nucleotides.
It is active against gram-positive microorganisms: Escherichia coli, Selenomonas, Streptococcus salivarius, Streptococcus mutans, anaerobes and fungi of the genus Candida albicans, to a lesser extent - gram-negative microorganisms: Pseudomonas, Proteus, Streptococcus sanguis, Klebsiella spp., Veillonella species.