Included in the formulation
Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):VED
ONLS
Minimal chemist's assortment
АТХ:H.02.A.B.09 Hydrocortisone
Pharmacodynamics:The drug is for external use.
By inhibition of phospholipase A activity2 and reducing the release of arachidonic acid from the phospholipids of cell membranes reduces the production of leukotrienes and prostaglandins. Due to this suppresses the development of inflammatory manifestations: pain, swelling, fever and redness in the area of inflammation. It inhibits the expression of the cyclooxygenase-2 gene, which also leads to inhibition of prostaglandin synthesis.
Reduces the main substance of the connective tissue, weakening the exudative and proliferative processes in the skin. Inhibits cellular kinins, which have proteolytic activity. Prevents the access of macrophages and T-sensitized lymphocytes to the foci of inflammation.
It has anti-inflammatory, anti-edematous and anti-allergic effect.
Pharmacokinetics:The drug for topical application, systemic action on the body does not.
Indications:
It is used for the treatment of pyoderma, atopic dermatitis, eczema, psoriasis.
XII.L20-L30.L20 Atopic dermatitis
XII.L20-L30.L20.8 Other atopic dermatitis
XII.L20-L30.L23 Allergic contact dermatitis
XII.L20-L30.L24 Simple irritant contact dermatitis
XII.L40-L45.L40 Psoriasis
XII.L20-L30.L30.3 Infectious dermatitis
Contraindications:
Viral infections and skin tuberculosis, syphilis, acne, fungal and precancerous skin diseases, perioral dermatitis, individual intolerance, children under 6 months.
Carefully:
Hypersensitivity.
Pregnancy and lactation:Recommendations for the FDA - Category B. It is used during pregnancy and lactation.
Dosing and Administration:Externally, lipocream is applied to the affected skin 1-3 times a day.
The maximum dose used during the week is 60 g.
Side effects:Allergic reactions. With prolonged use - acne, stria, skin atrophy.
Overdose:
Cases of overdose are not described.
Treatment is symptomatic.
Interaction:
Clinically significant interactions are not described.
Special instructions:It is not recommended to vaccinate during treatment.