Combined drug.
Glucosamine
Stimulates the development of matrix cartilage tissue, promotes regeneration processes, has a moderate anti-inflammatory effect.
Ibuprofen
Non-selective reversible cyclooxygenase inhibitor, an enzyme that catalyzes the reaction of the conversion of arachidonic acid to prostaglandin H2, which is the precursor of the remaining prostaglandins, thromboxane A2 and prostacyclin. Has anti-inflammatory and analgesic, as well as antipyretic effect. It inhibits the aggregation of platelets.
Ibuprofen also inhibits the synthesis of leukotrienes, reduces bradykinin activity, stabilizes lysosomal membranes. With articular syndrome reduces the severity of arthralgia (at rest and during movement), morning stiffness and swelling of the joints, helps reduce the degree of their functional insufficiency.
Chondroitin sulfate
It is the main component of proteoglycans, which together with collagen fibers constitute the matrix of cartilage. It acts as a chondroprotector, suppresses the activity of enzymes that promote degradation of the cartilaginous surface of the joint, activates metabolism in the subchondral bone, stimulates the production of proteoglycans by chondrocytes, and regenerates cartilage tissue. Has analgesic and anti-inflammatory effect, inhibits the secretion of prostaglandin E2 and leukotriene B4, reduces the excretion of inflammatory mediators in the synovial fluid.
Prevents the collapse of connective tissue, promotes the restoration of articular surfaces, improves the production of intraarticular fluid, which improves mobility in the joint and reduces the intensity of pain.