Glucosaminylmuramyl dipeptide (Glucoseminylmuramildipeptidum)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Other immunomodulators

Included in the formulation
  • Lycopid®
    pills inwards 
    PEPTEK, AO     Russia
    • АТХ:

    L.03.A.X   Other immunostimulants

    Pharmacodynamics:

    Synthetic analogue of the bacterial cell peptidoglycan. Affects the receptors of T-lymphocytes and phagocytes, activating their activity. Increases congenital and acquired immunity, strengthens protection against fungal, viral and bacterial infections.

    Pharmacokinetics:

    After oral administration, up to 13% is absorbed in the gastrointestinal tract. The maximum concentration in the blood plasma is reached after 1.5 hours. The connection with plasma proteins is 3-4%.

    Metabolism in the liver.

    The half-life is 4 hours. Elimination by the kidneys.

    Indications:

    It is used in the complex treatment of diseases that cause a state of secondary immunodeficiency: chronic infections and pulmonary tuberculosis, herpetic, papillomavirus infections, psoriasis, chronic hepatitis B and C.

    ICD-10

    I.A15-A19.A15   Tuberculosis of respiratory organs, confirmed bacteriologically and histologically

    I.B00-B09.B00   Infections caused by the herpes simplex virus [herpes simplex]

    I.B00-B09.B00.5   Herpetic eye disease

    I.B00-B09.B02.3   Shingles with eye complications

    I.B15-B19.B18.2   Chronic viral hepatitis C

    I.B15-B19.B18.1   Chronic viral hepatitis B without delta-agent

    I.B95-B97.B97.7   Papillomaviruses as a cause of diseases classified elsewhere

    X.J10-J18.J15   Bacterial pneumonia, not elsewhere classified

    X.J30-J39.J31   Chronic rhinitis, nasopharyngitis and pharyngitis

    X.J30-J39.J32   Chronic Sinusitis

    X.J30-J39.J35.0   Chronic tonsillitis

    X.J30-J39.J37   Chronic laryngitis and laryngotracheitis

    X.J40-J47.J42   Chronic bronchitis, unspecified

    XII.L00-L08.L01   Impetigo

    XII.L00-L08.L02   Abscess of skin, boil and carbuncle

    XII.L00-L08.L03   Phlegmon

    XII.L00-L08.L08.0   Pyoderma

    XII.L40-L45.L40   Psoriasis

    XIX.T79.T79.3   Post-traumatic wound infection, not elsewhere classified

    Contraindications:Autoimmune thyroiditis, febrile reaction, individual intolerance, children under 12 months.

    Carefully:Hypersensitivity.

    Pregnancy and lactation:Recommendations for FDA - Category C. Contraindicated in pregnancy and lactation.

    Dosing and Administration:

    Use in children

    At the age of 1 to 16 years: inside, 1 mg 1-3 times a day.

    Adults

    Sublingually, 2 mg 1-3 times a day.

    The highest daily dose: 6 mg.

    The highest single dose: 2 mg.

    Side effects:

    Feverish reaction.

    Digestive system: rarely - diarrhea.

    Allergic reactions.

    Overdose:

    Cases of overdose are not described.

    Treatment is symptomatic.

    Interaction:

    Strengthens the action of antimicrobial, antiviral and antifungal drugs.

    Special instructions:

    The dosage form contains sucrose and lactose.

    Instructions
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