Combined drug with antiproliferative and antibacterial action.
Isotretinoin
Biologically active form of vitamin A has anti-inflammatory, antiseboric, keratolytic action. Stimulates the growth and differentiation of epithelial cells. It inhibits terminal differentiation of sebocytes and hyperproliferation of the sebaceous gland ducts, normalizes the composition of their secretions, facilitating its excretion. Reduces the inflammatory reaction around the sebaceous glands, reduces the production of sebum. It inhibits follicular keratinization, prevents the formation of acne caused by Propionibacterium acnes.
Erythromycin
Antibiotic from the group of macrolides. It disrupts the synthesis of microbial proteins at the level of the ribosomes, by binding to 50Sthe subunit of bacterial ribosomes, inhibits the process of translocation. It penetrates into cells and creates a high intracellular concentration.
Has a bacteriostatic effect, in high concentrations has a bactericidal effect against the causative agents of diphtheria and pertussis, as well as pneumococci.
Has a high activity against gram-positive cocci (staphylococci, streptococci).
Erythromycin also exhibits high activity against chlamydia, leptospira, treponem, mycoplasma and toxoplasma.