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Dosage form: & nbspear drops
Composition:

Each milliliter contains:

Active substances: chloramphenicol 50.0 mg, beclomethasone dipropionate (anhydrous) 0.25 mg, clotrimazole 10.0 mg, lidocaine hydrochloride monohydrate, converted to lidocaine hydrochloride 20.0 mg.

Excipients: glycerol, propylene glycol.

Description:

Transparent liquid of light yellow color.

Pharmacotherapeutic group:Corticosteroids in combination with antimicrobials
ATX: & nbsp
  • Corticosteroids in combination with antimicrobials
  • Pharmacodynamics:

    Antimicrobial local, antibacterial, anti-inflammatory local, local anesthetic.

    Clotrimazole (imidazole derivative) is a broad-spectrum antifungal agent for topical application. The antifungal effect of clotrimazole is associated with a disruption in the synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the permeability of the membrane and causes subsequent cell lysis. Chloramphenicol bacteriostatic broad-spectrum antibiotic. Disrupts the process of protein synthesis in a microbial cell. It is active against gram-positive and gram-negative bacteria.

    Beclomethasone dipropionate is a glucocorticosteroid.Has anti-inflammatory and anti-allergic effect.

    Lidocaine - places about an anesthetic. It causes a reversible blockade of impulse conduction through nerve fibers due to blocking the passage of sodium ions through the membrane.

    Pharmacokinetics:

    Pharmacokinetics studies were not conducted.

    Indications:

    Allergic and inflammatory diseases of the ear, including:

    - acute diffuse external otitis media;

    - acute otitis media of the middle ear;

    - chronic otitis in the acute stage;

    - condition after surgical interventions on the ear.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Children's age (up to 6 years).

    Violation of the integrity of the tympanic membrane.

    Pregnancy and lactation:

    The question of the appropriateness of prescribing during pregnancy should be decided individually after consulting a doctor. The administration of the drug is possible if the intended benefit to the mother exceeds the potential risk to the fetus.

    Dosing and Administration:

    Before opening the package and the first use of the drug, it is necessary to warm the bottle in the hand for 3-5 minutes, to room temperature.With further use and storage at room temperature, additional warming is not required.

    Locally. Bury in the external ear canal for 4-5 drops 3-4 times a day. Improvement of the condition occurs within 3-5 days. The course of treatment is 7-10 days.

    Side effects:

    In rare cases, itching, burning in the place of application of the drug. Allergic reactions are possible.

    Interaction:Not studied.
    Form release / dosage:

    Ear drops.

    Packaging:5 ml in a bottle of dark glass, closed with a screw-on aluminum cap with the control of the first opening. A pipette inserted into the plastic screw cap is attached to the vial. Each bottle, complete with a pipette, placed in a sealed plastic bag, and the instructions for use are placed in a cardboard box.
    Storage conditions:

    Store in protected from light at a temperature of 2 to 8 ° C. Do not freeze.

    After opening the package, store at a temperature of no higher than 30 ° C for not more than 1 month.

    Keep out of the reach of children.

    Shelf life:2 years. Do not use after expiry date.
    Terms of leave from pharmacies:On prescription
    Registration number:П N014930 / 01
    Date of registration:16.05.2008 / 28.03.2017
    Expiration Date:Unlimited
    The owner of the registration certificate:Glenmark Pharmaceuticals Co., Ltd.Glenmark Pharmaceuticals Co., Ltd. India
    Manufacturer: & nbsp
    Representation: & nbspGLENMARK IMPEX LLCGLENMARK IMPEX LLCRussia
    Information update date: & nbsp21.11.2017
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