Included in the formulation
АТХ:R.01.A.B Sympathomimetics in combination with other drugs (excluding corticosteroids)
Pharmacodynamics:Combined drug. Phenylephrine (alpha-adrenomimetic) has a vasoconstrictive effect, which leads to a reduction in edema and hyperemia of the mucous membranes of the upper respiratory tract and accessory sinuses. Carbinoxamine has antihistamine action, it has moderately pronounced cholinolytic activity. Reduces the severity of local exudative manifestations, reduces the permeability of capillaries of the mucous membrane of the nasal cavity. Eliminates the phenomenon of rhinitis, burning in the eyes, a feeling of heaviness in the head for 10-12 hours.
Pharmacokinetics:No data.
Indications:- Acute rhinitis (vasomotor, allergic, infectious-inflammatory);- sinusitis;
- hay fever.
X.J00-J06.J00 Acute nasopharyngitis (runny nose)
X.J00-J06.J01 Acute Sinusitis
X.J30-J39.J30.0 Vasomotor rhinitis
X.J30-J39.J30.3 Other allergic rhinitis
X.J30-J39.J30.1 Allergic rhinitis caused by pollen of plants
Contraindications:hypersensitivity;- arterial hypertension;
- thyrotoxicosis;
- pheochromocytoma;
- an angle-closure glaucoma;
- hypertrophy of the prostate;
- Pregnancy;
lactation period.
Carefully:Severe renal dysfunction. Childhood.
Pregnancy and lactation:The action category for fetus by FDA is C. Studies in animals and adequate good controlled studies in pregnant women have not been conducted. Contraindicated in pregnancy and lactation. There is no data on the penetration of the drug into breast milk.
Dosing and Administration:Adults and children over 12 years - 1 capsule 2 times a day (in the morning and in the evening, with an interval of 12 hours). Capsules swallowed whole, not liquid. In case of difficulty swallowing appoint a syrup. Application in elderly patients
Use in the elderly has not been systematically studied. There is no data on the need to change the dosage of the drug in patients of this group compared to other patients. Due to age-related changes in the central nervous system, heart and vessels, kidneys, liver, correction and individual dose selection may be required.
Use in children
Data on use in children under the age of 12 years are absent.
Side effects:Dryness of the oral mucosa, decreased appetite, indigestion, visual impairment, dizziness, headache, insomnia, anxiety,inhibition, palpitations, cardialgia, increased blood pressure, changes in the pattern of peripheral blood, skin allergic reactions.
Overdose:Symptoms: in children and senile age - CNS excitation.
Interaction:Incompatible with MAO inhibitors; The adrenomimetic effect is enhanced by the background of guanethidine and isobarine. Halothane increases the risk of arrhythmia.
Special instructions:No data.