The security profile presented below is based on data collected in
The result is the observation of more than 5300 patients.
Frequency of occurrence of undesirable phenomena is determined as follows:
very often:> 10%
often:> 1% and <10%
sometimes:> 0.1% and <1%
rarely:> 0.01% and <0.1%
very rarely: <0.01%,
Clinical Trials Data:
Infections and infestations: sometimes - infections of the upper respiratory tract, rhinitis.
From the side of metabolism and nutrition: often - loss of appetite.
Neurological and psychiatric disorders: very often - irritability, headache; often drowsiness; sometimes - dizziness; rarely - reduced sensitivity, parasthesia.
From the gastrointestinal tract: often - gastrointestinal symptoms (such as diarrhea, nausea, vomiting).
From the skin and subcutaneous fat: sometimes - a rash; rarely - itching.
From the osteomuscular system and connective tissue: sometimes - myalgia, musculoskeletal tension.
General and local reactions: very often - pain and redness at the injection site, fatigue; often - malaise, fever (> 37.5 ° C), swelling and tightness in. place of administration; sometimes - influenza-like symptoms; rarely - chills.
Post-production data:
From the immune system: anaphylaxis, allergic reactions, including anaphylactoid reactions and allergic symptoms reminiscent of those with serum sickness.
From the nervous system: convulsions.
From the cardiovascular system: vasculitis.
From the skin and subcutaneous fat: angioedema, urticaria, erythema multiforme.
From the osteomuscular system and connective tissue: arthralgia.