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Dosage form: & nbspointment for external use
Composition:

Active substances:

Chondroitin sodium sulfate (in terms of dry matter)

5.0 grams

Diclofenac sodium

0.5 g

Dimethylsulfoxide (Dimexide)

10.0 grams

Excipients:

lanolin

10.0 grams

pentaerythritol dioleate (pentol)

5.0 grams

stearin

3.0 g

petrolatum

35.0 grams

purified water

up to 100 g

Description:

Ointment is light yellow with a brownish tinge, with a weak specific smell.

Pharmacotherapeutic group:reparation of tissue stimulant + NSAIDs
ATX: & nbsp
  • Other drugs for external use in pain syndrome with diseases of the musculoskeletal system
  • Pharmacodynamics:

    Combined drug, the action of which is determined by the active components that make up its composition.

    The current beginning is chondroitin sulfate, obtained from the cartilaginous tissue of the trachea of ​​cattle. Accelerates the synthesis of glycosaminoglucans. Participates in the construction of the basic substance of bone and cartilaginous tissue. Accelerates the recovery of bone tissue, inhibits the process of degeneration of cartilaginous tissue and stimulates the regeneration of articular cartilage. Prevents the compression of connective tissue. Normalizes the metabolism of hyaline tissue and the production of articular fluid. Has analgesic and anti-inflammatory effect.

    Diclofenac sodium has pronounced analgesic and anti-inflammatory properties. Indiscriminately inhibiting cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation. Diclofenac It is used to eliminate the pain syndrome and reduce the swelling associated with the inflammatory process.

    Dimexide has the ability to penetrate biological membranes, including through skin barriers, has a moderate antiseptic, analgesic and anti-inflammatory effect.

    Pharmacokinetics:It penetrates well through the skin, accumulates in the underlying tissues.
    Indications:

    Post-traumatic inflammation of soft tissues and joints, for example due to stretching, overstrain and bruises.

    Pain and swelling associated with diseases of the muscles and joints, degenerative joint and spinal diseases: rheumatoid arthritis, lumbago, sciatica, osteoarthritis, low back pain, ankylosing spondylitis.

    Contraindications:

    If you have any of these diseases, consult a doctor before taking the drug.

    Hypersensitivity, a complete or incomplete combination of bronchial asthma, recurrent polyposis of the nasal mucosa and paranasal sinuses and intolerance to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (including history), pregnancy (III trimester), lactation period, children's age (up to 12 years) , a violation of the integrity of the skin in the place of the intended application.

    Carefully:

    Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe violations of the liver and kidney function, chronic heart failure, bronchial asthma, elderly age, pregnancy I and II trimester.

    Pregnancy and lactation:The drug should not be used in the III trimester of pregnancy. Experience in using the drug during lactation is not available. Use in I and II trimesters is possible only after consultation with a doctor.
    Dosing and Administration:

    Outwardly.

    Adults and children over 12 years of age ointment applied to the skin 2-3 times a day, rubbing it until completely absorbed for 2-3 minutes.

    The course of treatment is 2-3 weeks. If necessary, the course can be repeated.
    Side effects:

    Local Reactions: eczema, contact dermatitis (itching, redness, swelling of the treated area of ​​the skin, papules, vesicles, peeling).

    Systemic reactions: generalized skin rash, allergic reactions (urticaria, angioedema, bronchospastic reactions), photosensitization.

    If any of the side effects indicated in the manual are aggravated or you notice any other side effects not listed in the instructions, inform your doctor.
    Interaction:The drug may enhance the effect of drugs that cause photosensitivity.
    Special instructions:

    Ointment should be applied only to intact skin, avoiding getting on open wounds.

    After applying, do not apply an occlusive dressing.

    Do not allow the drug to enter the eyes and mucous membranes.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not adversely affect the performance of potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions, as well as vehicle management.

    Form release / dosage:

    Ointment for external use.

    Packaging:

    For 30 g in tubes of aluminum or polymer.

    One tube together with the instruction for use is placed in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of no higher than 20 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-002563
    Date of registration:02.06.2011
    The owner of the registration certificate:BIOSINTEZ, PAO BIOSINTEZ, PAO Russia
    Manufacturer: & nbsp
    Representation: & nbspBIOSINTEZ JSC BIOSINTEZ JSC Russia
    Information update date: & nbsp29.02.2016
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