WHO classification: very often - 1/10 appointments, often - 1/100 appointments, not often - 1/1000 appointments, rarely - 1/10000 appointments, very rarely - less than 1/10000 appointments.
Lercanidipine + enalapril
From the central nervous system: often - dizziness; not often - a headache.
From the side of the psyche: not often - anxiety.
From the skin: not often - dermatitis, edema of the lips, erythema, urticaria, rash.
From the genitourinary system: not often - erectile dysfunction.
From the urinary system: not often - pollakiuria, polyuria, nocturia.
From the immune system: not often - hypersensitivity to one of the components of the drug, Quincke's edema.
From the side of metabolism: not often - hypertriglyceridemia.
From the musculoskeletal system: not often - arthralgia.
From the digestive system: not often - abdominal pain, nausea, constipation, dyspepsia, glossitis.
On the part of the hematopoiesis system: not often - thrombocytopenia.
From the respiratory system: often - cough; not often - dryness in the throat, pharyngeal and throat pain.
From the cardiovascular system: often - "tides" of blood to the skin of the face; not often - a feeling of palpitations and tachycardia, a pronounced decrease in blood pressure, a circulatory collapse, a congestive cardiac failure.
From the side of the hearing organ and labyrinthine disorders: often - vertigo, including positional vertigo.
Laboratory indicators: not often - a decrease in the level of hemoglobin, an increase in ALT (alanine transferase) activity, ACT (asparagine transferase).
Other: often - peripheral edema, not often - asthenia, increased fatigue, a feeling of heat.
Enalaprooze
From the central nervous system: very often - dizziness; often - headache; not often - paresthesia.
From the side of the psyche: often - depression; not often - confusion, drowsiness, insomnia, nervousness; rarely - pathological dreams, sleep disturbance.
From the skin: often - a rash; not often - increased sweating, itching, hives, alopecia; rarely - erythema multiforme, exfoliative dermatitis, Stevens-Jones syndrome, Lyell syndrome, pemphigus.
From the urinary system: not often - renal insufficiency, proteinuria; rarely - oliguria.
From the genitourinary system: not often - erectile dysfunction; rarely - gynecomastia.
From the immune system: often - hypersensitivity, angioedema, swelling of the face, extremities, lips, tongue, glottis and / or larynx; rarely - autoimmune disorders.
From the side of metabolism: not often - hypoglycemia, anorexia.
From the musculoskeletal system: not often - muscle spasm.
From the digestive system: very often - nausea; often - diarrhea, abdominal pain, impaired taste; infrequent - intestinal obstruction, pancreatitis, vomiting, dyspepsia, constipation, dryness of the oral mucosa, stomach pain, stomach or duodenal ulcer; rarely - stomatitis, aphthous stomatitis, glossitis; very rarely - intestinal angioedema.
From the liver and bile ducts: rarely - liver failure, hepatitis - cholestatic or necrotic, cholestasis.
On the part of the hematopoiesis system: not often - anemia, including aplastic and hemolytic; rarely - thrombocytopenia, neutropenia, agranulocytosis, pancytopenia, lymphadenopathy, insufficiency of bone marrow hematopoiesis.
From the respiratory system: very often - cough; often shortness of breath; not often - rhinorrhea, pharyngeal-laryngeal pains, dysphonia, bronchospasm, asthma; rarely - lung infiltration, rhinitis, alveolar allergic / eosinophilic pneumonia.
From the side of the organ of vision: very often - reduced visual acuity.
From the side of the hearing organ and labyrinthine disorders: not often - ringing in the ears, vertigo.
From the cardiovascular system: often - arrhythmia, angina pectoris, tachycardia, myocardial infarction, marked decrease in blood pressure, fainting, stroke, due to excessive lowering of blood pressure in patients with increased risk; not often - a feeling of palpitation, "hot flashes" of blood to the skin of the face, orthostatic hypotension; rarely - Raynaud's syndrome.
Laboratory indicators: often - hyperkalemia,increase in creatinine in the blood; not often - an increase in urea in the blood, a decrease in the sodium content in the blood; rarely - an increase in the level of hemoglobin and hematocrit, an increase in the number of hepatic enzymes and a decrease in the concentration of bilirubin in the blood.
Other: very often - asthenia; often - fatigue, chest pain; not often - malaise.
A symptom complex including facial flushing, nausea, vomiting, and a marked decrease in blood pressure is also described and can develop with concomitant use of ACE inhibitors and a gold preparationsodium aurotomy malate) intravenously.
Lercanidipine
From the central nervous system: not often - dizziness, headache.
From the side of the psyche: rarely - drowsiness.
From the skin: rarely - a rash.
From the immune system: very rarely - increased sensitivity.
From the urinary system: rarely - polyuria.
From the musculoskeletal system: rarely - myalgia.
From the digestive system: rarely - nausea, dyspepsia, diarrhea, abdominal pain, vomiting.
From the cardiovascular system: not often - tachycardia, palpitation, "hot flashes" of blood to the skin of the face; rarely - angina pectoris; very rarely - faint.
Other: not often - peripheral edema; rarely - asthenia, increased fatigue.