Active substanceTyloronTyloron
Similar drugsTo uncover
  • Aktaviron
    pills inwards 
    ZIO-HEALTH, JSC     Russia
  • Amiksin®
    pills inwards 
  • Lavomax®
    pills inwards 
    NIZHFARM, JSC     Russia
  • ORVIS® Immuno
    pills inwards 
    EVALAR, CJSC     Russia
  • Tilaxin®
    pills inwards 
    DALHIMFARM, OJSC     Russia
  • Tiloram
    pills inwards 
    ATOLL, LLC     Russia
  • Tyloron
    pills inwards 
    ATOLL, LLC     Russia
  • Tyloron
    capsules inwards 
  • Tyloron-SZ
    pills inwards 
    NORTH STAR, CJSC     Russia
  • Dosage form: & nbspcoated tablets
    Composition:

    One tablet contains:

    core:

    active substance - Tilorone dihydrochloride - 125 mg; Excipients: magnesium hydroxycarbonate (magnesium carbonate heavy), povidone KZO, calcium stearate;

    sheath: sucrose, povidone K17, copovidone, magnesium hydroxycarbonate (magnesium carbonate light), titanium dioxide, silicon dioxide colloid (aerosil A-380), dye quinoline yellow, dye sunset yellow, macrogol-6000, beeswax, paraffin liquid, talc.

    Description:
    The tablets covered with a cover, from yellow up to orange color, the round form. The core of the tablet is orange.
    Pharmacotherapeutic group:Antiviral immunostimulating agent - inducer of interferon formation
    ATX: & nbsp

    L.03.A.X   Other immunostimulants

    Pharmacodynamics:

    A low-molecular synthetic interferon inducer that stimulates the formation of all types of interferons in the body (alpha, beta, gamma and lambda). The main producers of interferon in response to the introduction of Tyloron are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils and granulocytes. After oral administration, the maximum production of interferon is determined in the sequence of the intestine - liver - blood after 4-24 hours. Tyloron has immunomodulatory and antiviral effect.

    According to experimental studies, after a single oral administration of tylorone in a dose equivalent to the maximum daily dose for a person, the maximum concentration in the lung tissue of interferon lambda is determined after 24 hours, interferon alpha - after 48 hours. Induction of interferon lambda in the lung tissue contributes to an increase in antiviral protection of the respiratory tract in influenza and other respiratory viral infections.

    In human leukocytes induces the synthesis of interferon.Stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors and T-helpers. Effective against various viral infections, including against influenza viruses, other acute respiratory viral infections, hepatitis viruses and herpesviruses. The mechanism of antiviral action is associated with the inhibition of the translation of virus-specific proteins in infected cells, as a result of which the reproduction of viruses is suppressed.

    Pharmacokinetics:
    After oral administration tilorone quickly absorbed from the gastrointestinal tract. Bioavailability is 60%. About 80% of Tyloron binds to plasma proteins. Displayed tilorone almost unchanged through the intestine (70%) and through the kidneys (9%). The half-life is 48 hours. Tyloron does not undergo biotransformation and does not accumulate in the body.
    Indications:

    As part of complex therapy in adults:

    - treatment of influenza and other ARVI;

    treatment of herpetic infection.

    Prevention of influenza and other acute respiratory viral infections in adults.

    Contraindications:

    Hypersensitivity to tilorone or other components of the drug.

    Pregnancy and lactation.

    Children's age (up to 18 years).

    Deficiency of sugar / isomaltase, intolerance to fructose, glucose-galactose malabsorption (the preparation contains sucrose).

    Pregnancy and lactation:The use of the drug during pregnancy is contraindicated. If it is necessary to use the drug during lactation, breastfeeding should be discontinued.
    Dosing and Administration:

    The drug is taken orally after a meal.

    To treat influenza and other ARVI - 125 mg per day in the first 2 days of treatment, then 125 mg after 48 hours. On the course - 750 mg (6 tablets).

    For the prevention of influenza and other ARVI - 125 mg once a week for 6 weeks. On the course - 750 mg (6 tablets).

    For the treatment of herpetic infection - the first two days of 125 mg, then 48 hours after 125 mg. The course dose is 1.25-2.5 g (10-20 tablets).

    When treating influenza and other acute respiratory viral infections, if symptoms persist for more than 4 days, consult a doctor.

    Side effects:

    Allergic reactions, dyspeptic phenomena, short-term chills are possible.

    If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

    Overdose:
    Cases of overdose with Lavomax® are unknown.
    Interaction:

    Compatible with antibiotics and traditional treatment of viral and bacterial diseases.

    Clinically significant interaction of Lavomax ® with antibiotics, traditional treatment of viral and bacterial diseases, alcohol was not detected.

    Effect on the ability to drive transp. cf. and fur:
    The use of the drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:
    Tablets coated with a coating, 125 mg.
    Packaging:
    For 3, 4, 6 or 10 tablets in a contour cell package. One or two contouring packagings together with instructions for the use of the drug are placed in a cardboard pack.
    Storage conditions:

    In a dry, protected from light place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:
    2 years. Do not use the product after the expiry date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N003749 / 01
    Date of registration:28.09.2009 / 30.03.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:NIZHFARM, JSC NIZHFARM, JSC Russia
    Manufacturer: & nbsp
    Representation: & nbspNizhpharm, JSCNizhpharm, JSCRussia
    Information update date: & nbsp08.02.2018
    Illustrated instructions
      Instructions
      Up