Lickferr-Folly (Likferr-Folly)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIron (III) hydroxide polymaltosate + Folic acidIron (III) hydroxide polymaltosate + Folic acid
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  • Lickferr-Folly
    capsules inwards 
    FarmSirma Soteks, ZAO     Russia
  • Maltofer® Foul
    pills inwards 
    Vifor (International) Inc.     Switzerland
    • Dosage form: & nbspcapsules
    Composition:

    One capsule contains iron [III] hydroxide polymaltosate 370.4 mg in terms of elemental iron 100 mg and 550 μg of folic acid.

    Excipients: magnesium stearate, paraffin liquid, sodium lauryl sulfate, lactose, capsule shell: sodium lauryl sulfate, gelatin, methyl parahydroxybenzoate, propyl parahydroxybenzoate, water, crimson dye [Ponso 4R], dye azorubin, titanium dioxide.

    Description:Hard gelatin capsules No. 2, dark red. The contents of capsules are a powder of dark brown color with inclusions of white or almost white color.
    Pharmacotherapeutic group:Anti-anemic agent. Preparation of iron + vitamin
    ATX: & nbsp

    B.03.A.D.   Preparations of iron in combination with folic acid

    Pharmacodynamics:

    Combined anti-anemic drug, the effect of which is due to the properties of the components that make up its composition.

    In the preparation, iron is in the form of a complex compound of iron [III] hydroxide with polymaltose. This macromolecular complex is stable and does not release iron in the form of free ions.The complex is similar in structure to the natural iron-ferritin compound, so that when ingested, iron [III] from the intestine enters the blood by active absorption, which makes it practically impossible to overdose and poison the drug. Iron [III] hydroxide polymaltose complex does not possess the prooxidant properties that are inherent in iron (II) salts. Transport of iron in plasma is carried out with the help of gamma globulin transferrin, synthesized in the liver. Iron in combination with transferrin is transferred to the cells of the body, where it is used for the synthesis of hemoglobin, myoglobin and some enzymes. The absorbed iron is retained in the ferritin-related form, mainly in the liver. Trivalent iron participates in the formation of heme, which leads to an increase in the level of hemoglobin.

    Folic acid is a vitamin of group B. It is necessary for normal maturation of megaloblasts and the formation of normoblasts. Stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines and pyrimidines, in the exchange of choline.

    Indications:
    • Treatment of latent and clinically pronounced iron deficiency (iron deficiency anemia).
    • Prevention of iron deficiency and folic acid, including, before, during pregnancy and lactation.
    Contraindications:
    • Hypersensitivity;
    • Children up to 12 years;
    • Diseases accompanied by the accumulation of iron in the body (hemosiderosis, hemochromatosis);
    • Disturbances in the assimilation of iron (sidero-sacrificial anemia, lead anemia, thalassemia);
    • Anemias that are not associated with deficiency of iron or folic acid (megaloblastic or hemolytic anemia).
    Pregnancy and lactation:

    During controlled studies in pregnant women (2nd - 3rd trimester of pregnancy), there was no adverse effect on the mother and fetus organisms. There was no adverse effect on the fetus when taking drugs in the first trimester of pregnancy.

    Dosing and Administration:

    The dosage of Likferr-Folly and the duration of treatment depend on the severity of iron deficiency. The drug is prescribed 1 capsule per day inside during or immediately after meals.

    Children over 12 years of age, adults and nursing mothers with severe iron or folate deficiency the dose is increased to 2-3 capsules per day. The drug should be treated prior to the normalization of the picture of peripheral blood (8-12 weeks).Maintenance therapy is performed for at least 4 weeks after reaching the normal level of hemoglobin (1 capsule per day).

    Pregnant women should take 1 capsule of Lycferr-Folly 2-3 times a day before the normalization of hemoglobin. Next, continue taking the drug 1 capsule a day before delivery to restore iron stores.

    For the prevention of iron deficiency and folic acid and therapy of latent iron deficiency, patients should take 1 capsule of the drug per day. The duration of treatment of latent iron deficiency is 4-8 weeks.

    Side effects:

    Rarely.

    On the part of the digestive system: in some cases - a feeling of stomach overflow, discomfort, nausea, constipation or diarrhea, allergic reactions to folic acid.

    When applying the drug, dark staining of the stool can appear, which is not of clinical significance.

    Overdose:

    When an overdose of the drug signs of poisoning and iron overload were not observed.

    Interaction:

    No interaction with other drugs was noted.

    Special instructions:

    One capsule of Lycferr-Folly contains 0,04 bread units, which must be taken into account when appointing patients with diabetes.

    Form release / dosage:

    Capsules.

    Packaging:For 10 or 20 capsules in a blister of PVC and aluminum foil. For 2 or 4 blisters with instructions for use are placed in a cardboard bundle.
    Storage conditions:

    At a temperature of no higher than 25 ° C in a dry place.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use later than the date shown on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-001882/07
    Date of registration:02.08.2007 / 21.07.2014
    Expiration Date:Unlimited
    The owner of the registration certificate:FarmSirma Soteks, ZAO FarmSirma Soteks, ZAO Russia
    Manufacturer: & nbsp
    Representation: & nbspPharm Company Sotex CJSC Pharm Company Sotex CJSC Russia
    Information update date: & nbsp24.02.2018
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