Methylphenylthiomethyl-dimethylaminomethyl-hydroxybromoindole carboxylic acid ethyl ester (Methylphenylthiomethyl-dimethylaminomethyl-hydroxy-bromindol carbonic acid ethyl ester)

Clinical and pharmacological group: & nbsp

Other immunomodulators

Antiviral drugs (excluding HIV)

Included in the formulation
АТХ:

L.03.A.X   Other immunostimulants

Pharmacodynamics:

It has anti-influenza and immunomodulatory effects, suppresses influenza A and B viruses. When a virus attack prevents the fusion of the lipid envelope of the virus with the cell membranes. It induces the synthesis of interferon, stimulates cellular and humoral immune responses, increases the body's resistance to viral diseases.

It normalizes immunological indices and reduces the frequency of post-flu-like complications.

Pharmacokinetics:

After oral administration, it is rapidly absorbed in the gastrointestinal tract. The maximum concentration in the blood plasma is achieved after 1.2-1.5 h. Metabolism in the liver.

Half-life is 17-21 hours. About 40% is excreted in feces unchanged, mostly with bile. Elimination of the kidneys to 0.12%.

Indications:

It is used for the prevention and treatment of influenza A and B, for the treatment of acute respiratory viral infections, with secondary immunodeficiency states. It is used in the complex therapy of pneumonia, bronchitis and recurrent herpetic infection.

I.B00-B09.B00.9   Herpetic infection, unspecified

X.J10-J18.J15   Bacterial pneumonia, not elsewhere classified

X.J10-J18.J10.1   Influenza with other respiratory manifestations, influenza virus identified

X.J10-J18.J10   Influenza caused by an identified influenza virus

X.J40-J47.J40   Bronchitis, not specified as acute or chronic

X.J20-J22.J21.9   Acute bronchiolitis, unspecified

Contraindications:

Individual intolerance.

Carefully:

Lactase insufficiency.

Pregnancy and lactation:

Recommendations for FDA - Category C. Contraindicated in pregnancy and lactation.

Dosing and Administration:

Application in children

3-6 years: 50 mg 4 times / day;

6-12 years: 100 mg each. 4 times / day.

Dosing and Administration

Adults and children from 12 years: 200 mg 4 times / day every 6 hours for 5 days, then 200 mg once a week for 4 weeks.

The highest daily dose: 800 mg

The highest single dose: 200 mg.

Side effects:

Allergic reactions.

Overdose:

Not checked.

Interaction:

Clinically significant interactions are not described.

Special instructions:

It does not possess neurotropic activity, it can be used in healthy persons, including those whose occupations are connected with driving cars.

Instructions
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