Included in the formulation
АТХ:J.05.A.X Other antiviral drugs
Pharmacodynamics:Synthetic analogue of guanine with antiviral effect. Inhibits the replication of genomic fragments and the synthesis of viral RNA.
Pharmacokinetics:After oral administration, it is rapidly absorbed in the gastrointestinal tract. The maximum concentration in the blood plasma is reached after 1-1.5 hours.
The half-life is 1-1.5 hours. Elimination by the kidneys.
Indications:It is used to treat influenza in adults.
X.J10-J18.J12.9 Viral pneumonia, unspecified
X.J10-J18.J11.0 Influenza with pneumonia, virus not identified
X.J10-J18 Influenza and pneumonia
X.J10-J18.J10.8 Influenza with other manifestations, influenza virus identified
X.J10-J18.J11 Influenza, virus not identified
Contraindications:Severe renal and hepatic insufficiency.
Individual intolerance.
Carefully:High individual sensitivity to the drug.
Pregnancy and lactation:Recommendations for FDA - Category C. Contraindicated during pregnancy and lactation.
Dosing and Administration:Inside, regardless of the time of food intake, 250 mg (1 capsule) 3 times / day. The course of treatment is 5-7 days.
The highest daily dose: 750 mg.
The highest single dose: 250 mg.
Side effects:Dyspeptic disorders, allergic reactions.
Overdose:Nausea, vomiting, diarrhea.
Treatment is symptomatic.
Interaction:Simultaneous use with analogs of pyrimidine and purine bases may lead to an increase in the toxicity of the preparation.
When used simultaneously with ribavin, a dose reduction of ribavin is necessary.
Special instructions:The use of the drug gives a positive effect when taken no later than the second day after the onset of the disease.