Mode of application
Intended for intravenous administration only in the central veins.
The temperature of the emulsion to be introduced must correspond to room temperature.
The configuration of the chambers of the preparation Nutriflex 48/150 lipid allows to add the fat emulsion in the last turn, in order to preliminary assess the compatibility with other added drugs.
The technique of mixing the contents of the container chambers
If you need to add other drugs to the drug Nutriflex 48/150 lipid, use the following procedure:
1. Remove the secondary plastic bag from the container, unfold and place the container on a firm, level surface (on the table);
2. Having pressed two hands on the upper left chamber of the container (containing glucose solution with electrolytes), destroy the septum separating it from the lower chamber (containing a solution of amino acids with electrolytes);
3. If necessary, add electrolytes, microelements and other compatible medicinal preparations (including water-soluble vitamins) through an additional port with a red protective cap;
4. Having pressed two hands on the upper right chamber of the container (containing the fat emulsion), destroy the septum that separates it from the lower chamber;
5. If necessary, add fat-soluble vitamins through an additional port with a red protective cap;
6. Gently mix the contents of all the container chambers.
If there is no need to add other drugs to the drug Nutriflex 48/150 lipid, use the following procedure:
1. Remove the secondary plastic bag from the container, unfold and place the container on a firm, level surface (on the table);
2. Having pressed two hands on the two upper chambers of the container, destroy the partitions that separate them from the lower chamber;
3. Gently mix the contents of all the container chambers.
For infusion after mixing the contents of the container chambers:
- Moving the emulsion to the lower chamber, fold the container along the middle line separating the empty upper chambers from the lower one;
- Hang the container on the infusion rack for a special ring in the center of the container;
- Remove the white protective cap from the infusion port, connect the system for intravenous infusions and start infusion at the rate specified in these instructions for use.
Doses
Are selected according to individual needs.
Children from 14 years and adults
The maximum daily dose is 40 ml / kg of body weight, which corresponds to:
- 1.54 g of amino acids / kg of body weight / day,
- 4.8 g of glucose / kg of body weight / day,
- 1.6 g fat / kg body weight / day.
Children from 2 to 14 years old
These recommendations are based on average needs. The dose should be individually adapted depending on the age, stage of development and severity of the disease. To calculate the dose, it is necessary to take into account the degree of hydration of patients of childhood.
For children, it may be necessary to begin a diet with half the calculated dose. The dose should be increased to the maximum in stages in accordance with the individual metabolic capabilities of the body.
For children from 2 to 5 years The daily dose is 40 ml / kg of body weight, which corresponds to:
- 1.54 g of amino acids / kg of body weight / day,
- 4.8 g of glucose / kg of body weight / day,
-1.6 g fat / kg body weight / day.
For children from 5 to 14 years old The daily dose is 25 ml / kg of body weight, which corresponds to:
- 0.96 g of amino acids / kg of body weight / day,
- 3.0 g glucose / kg body weight / day,
- 1.0 g fat / kg body weight / day.
Due to the age-specific features of children, Nutriflex 48/150 lipid may not fully meet the energy need. In these cases, a glucose solution or fat emulsion can be added to the parenteral nutrition program as needed.
The rate of administration
It is recommended a long-term introduction of the drug Nutriflex 48/150 lipid. The stepwise increase in the rate of infusion during the first 30 minutes reduces the incidence of possible complications.
Maximum infusion rate - 2.0 ml / kg body weight / h, which corresponds to:
- 0.08 g of amino acids / kg of body weight / h,
- 0.24 g glucose / kg body weight / h,
- 0.08 g fat / kg body weight / h.
For a patient with a body weight of 70 kg, the maximum infusion rate is 140 ml / h. At the same time, the rate of introduction of amino acids is 5.4 g / h, glucose 16.8 g / h, fats 5.6 g / h.
The maximum energy intake should not exceed 40 kcal / kg of body weight / day.In special cases (for example, for patients with burns), this indicator can be increased.
Elderly patients
Doses do not differ from those recommended for other adult patients. Nevertheless, the metabolism can vary significantly in old age, so careful monitoring of this group of patients is necessary.
Patients with renal and / or liver failure
Doses are selected individually.
Duration of application
Duration of application of the drug Nutriflex 48/150 lipid is not limited. With prolonged use, it is necessary to add appropriate amounts of trace elements and vitamins.