Buckthorn leaves buckthorn extract (Extractum foliorum Hippophaes rhamnoides)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Antiviral drugs (excluding HIV)

Included in the formulation
  • Hyporamine
    raw materials.
    FARMTSENTR VILAR, ZAO     Russia
    • АТХ:

    D.06.B.B   Antiviral drugs

    Pharmacodynamics:

    Wound healing, antisclerotic, antioxidant (sea buckthorn oil), anticoagulant (sea buckthorn oil).

    The drug has antiviral activity against various strains of the influenza virus A and B, paramyxoviruses, adenoviruses, viruses Varicella zoster, Herpes simplex, cytomegalovirus, HIV, respiratory syncytial virus. It suppresses the activity of viral neuroiminidase, the effect on the reproduction of viruses is manifested in the early stages of their development. It induces the production of interferon.

    Pharmacokinetics:

    Not described.

    Indications:
    • Steamaflu.
    • Influenza A and B.
    • Angina on the background of acute respiratory viral infection, accompanied by rhinitis.
    • Respiratory syncytial ARVI.
    • Adenoviral ARVI.
    • Acute / recessive form of Herpes simplex of genital / extragenital localization.
    • Cytomegalovirus infection.
    • Chickenpox.
    • Herpes zoster.
    • Radiation lesions of the skin and mucous membranes.
    • Colpitis, endocervicitis, erosion of the cervix.
    • Peptic ulcer of stomach and duodenum, hyperacid gastritis, period after GI operations, chronic colitis, ulcerative colitis (as part of combination therapy).
    • Atrophic pharyngitis, laryngitis.
    ICD-10

    I.A50-A64.A60   Anogenital herpetic viral infection [herpes simplex]

    I.A50-A64.A60.9   Anogenital herpetic infection, unspecified

    I.B00-B09.B00   Infections caused by the herpes simplex virus [herpes simplex]

    I.B00-B09.B00.9   Herpetic infection, unspecified

    I.B00-B09.B01   Chicken Pox [varicella]

    I.B25-B34.B25   Cytomegalovirus

    I.B25-B34.B25.9   Cytomegalovirus disease, unspecified

    I.B95-B97.B97.0   Adenoviruses as a cause of diseases classified elsewhere

    X.J00-J06.J06.9   Acute upper respiratory tract infection, unspecified

    X.J10-J18.J10   Influenza caused by an identified influenza virus

    Contraindications:

    Hypersensitivity, age is less than 3 years. Pregnancy, breast-feeding.

    For oral administration: cholecystitis, cholangitis, pancreatitis, hepatitis, cholelithiasis. For rectal administration: diarrhea.

    Carefully:

    No data.

    Pregnancy and lactation:

    Category of recommendations for FDA is not defined. Adequate and well-controlled studies in humans and animals have not been conducted. There is no information on the penetration into breast milk. Do not apply.

    Dosing and Administration:

    Intranasally, inhalation, sublingually, vaginally, rectally, externally.

    Sublingually: 0.02 g 4-6 times a day.

    Inhalation: 0.02 g per 10 ml of water 2 times a day.

    External: 0.5% ointment at the site of the lesion 6 times a day.

    Rectal: 0.05 g 2 times a day.

    The course of treatment is from 3 days to 3 weeks, depending on the indications.

    Side effects:

    Allergic reactions. Bitterness in the mouth, burning (for external and rectal use), diarrhea, biliary colic.

    Overdose:

    Not described. Treatment is symptomatic.

    Interaction:

    Reduces the cytogenetic effect of cisplatin, pharmbubicin and cyclophosphamide.

    Special instructions:

    When prescribing a patient with diabetes mellitus, it should be borne in mind that 1 sublingual tablet contains 529.9 mg sucrose.

    Impact on the ability to drive vehicles and manage mechanisms not found.

    Instructions
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