Odeston (Odeston)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Active substanceGimecromoneGimecromone
Similar drugsTo uncover
  • Odeston
    pills inwards 
    Pabianicki Pharmaceutical Plant Polfa, JSC     Poland
    • Dosage form: & nbsppills
    Composition:

    Active substance: gimecromone - 200 mg

    Excipients: starch potato - 45 mg, gelatin - 3 mg, sodium lauryl sulfate - 1 mg, magnesium stearate - 1 mg.

    Description:

    Round, from white to white with a yellowish shade of color, flat-cylindrical tablets with a facet and engraving on one side with the letters "SI".

    Pharmacotherapeutic group:Cholagogue
    ATX: & nbsp

    A.05.A.X.02   Gimecromone

    Pharmacodynamics:

    Cholagogue preparation. Increases the formation and secretion of bile. Has a selective antispasmodic effect on the bile duct and sphincter of Oddi (does not reduce the peristalsis of the gastrointestinal tract (GIT)) and blood pressure (BP). Reduces stagnation of bile, prevents the crystallization of cholesterol and thus the development of cholelithiasis.

    Pharmacokinetics:

    When ingestion is easily absorbed from the digestive tract, weakly binds to plasma proteins. The maximum concentration in the blood serum is achieved in 2-3 hours. The half-life is about 1 hour. Gimecromone is excreted by the kidneys (about 93% in the form of glucuronate, 1.4% - sulfonate, 0.3% - unchanged).

    Indications:

    Dyskinesia of bile ducts and sphincter of Oddi in hyperkinetic type, noncalculous chronic cholecystitis, cholangitis,cholelithiasis; a condition after operative interventions on a cholic bubble and cholic ways. Decreased appetite, nausea, constipation, vomiting (on the background of hypoxecretion of bile).

    Contraindications:

    Hypersensitivity. Biliary tract obstruction, renal / hepatic insufficiency, ulcerative colitis, Crohn's disease, gastric ulcer and duodenal ulcer 12-, hemophilia. Children under 18 years.

    Pregnancy and lactation:

    There is no data on the safety of the use of gimecromone during pregnancy and lactation. The appointment of Odeston to pregnant women and during lactation is permissible only in those cases; when the potential benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Inside, 30 minutes before eating; adults - 200-400 mg three times a day. Suthe exact dose of 1200 mg. Course of treatment 2 of the week.

    In case of missing the dose, the drug should be taken as soon as possible or, if the next appointment is approaching, the missed dose should not be taken. Do not take a double dose at once.

    Side effects:

    Allergic reactions; diarrhea, flatulence, abdominal pain, expression of the mucous membrane of the gastrointestinal tract, headache.

    Overdose:

    There are no data on drug overdose in humans.

    Interaction:

    Morphine weakens the effect of gimecromone.

    When combined with metoclopramide, the effects of both drugs are weakened.

    Enhances the effects of indirect anticoagulants.

    Special instructions:

    Does not impair the secretory function of the digestive glands and intestinal absorption processes.

    Special precautions for the destruction of unused medicinal product
    Drugs should not be disposed of in sewers or in household waste containers. Ask the pharmacist how to dispose of the unused medication. These activities will help protect the environment.
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:

    Tablets of 200 mg.

    Packaging:

    For 10 tablets in a blister of PVC / Al.

    For 2, 5 or 10 blisters together with instructions for use in cardboard tutu.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use the drug with expired shelf life.

    Terms of leave from pharmacies:Without recipe
    Registration number:П N015046 / 01
    Date of registration:31.07.2008 / 01.07.2014
    Expiration Date:Unlimited
    The owner of the registration certificate:Pabianicki Pharmaceutical Plant Polfa, JSCPabianicki Pharmaceutical Plant Polfa, JSC Poland
    Manufacturer: & nbsp
    Representation: & nbspAdamed RASHA LLCAdamed RASHA LLCRussia
    Information update date: & nbsp22.05.2017
    Illustrated instructions
      Instructions
      Up