Included in the formulation
Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):VED
АТХ:J.06.B.B.02 Human tetanus antiglobulin
Pharmacodynamics:Neutralizes tetanus toxin.
Pharmacokinetics:After intramuscular injection, the maximum concentration in the blood plasma is reached after 24-48 hours.
The half-life is 3-4 weeks.
Indications:It is used for emergency prevention of tetanus in children and adults.
XXI.Z20-Z29.Z23.5 The need for immunization against tetanus alone
XXI.Z20-Z29.Z29.1 Prophylactic immunotherapy
Contraindications:Individual intolerance.
Carefully:Presence of allergic reactions in the anamnesis.
Pregnancy and lactation:Recommendations for FDA - category is not defined. It is used for life indications.
Dosing and Administration:Intramuscularly for the purpose of prevention: 250 IU for children and adults.
In the treatment of tetanus, the dose is 3-6 thousand IU: it is divided and injected into different places.
The highest daily dose: 6 thousand IU.
The highest single dose: 6 thousand IU.
Side effects:Local (edema, infiltration at the injection site) and allergic reactions.
Overdose:Cases of overdose are not described.
Treatment is symptomatic.
Interaction:Compatible with all drugs, including antibiotics.
Reduces the effectiveness of active immunization against rubella, chicken pox, measles, mumps. It is recommended to use antiviral vaccines 3 months after the application of the anti-staphylococcal immunoglobulin.
Special instructions:In case of emergency prophylaxis of tetanus immunoglobulin and anatoxin, drugs must be administered to different areas of the body using different syringes.