Intravenously, in the position of the patient lying or sitting.
Mandatory preliminary blockade of the thyroid gland with sodium iodide (100 mg per day) 3 days before the study and 2 days after the study.
Recommended doses: adult patients - 110-300 MBq.
If necessary, the drug can be diluted with 0.9% sodium chloride solution.
The diagnostic equipment is a gamma camera planar or rotational (SPECT) with a round (not less than 400 mm in diameter) or a rectangular crystal.
Adjustment of the amplitude analyzer 0.159 MeV, 20% window. The collimator should be used for energy above 0.15 MeV, since the X-ray radiation produced by the scattering of gamma quanta on the collimator material is not absorbed by the walls of the channels of the standard technetium collimator and the image becomes very noisy. Data collection and processing system - any of the existing data acquisition matrices of at least 128 × 128 elements.
Scintigraphy of the myocardium is carried out in 20-30 minutes and 4 hours after intravenous injection radiopharmaceutical in planar or rotary modes.The image processing on the computer includes background subtraction, 9-point smoothing or filtering with an adequate filter, correction of the frame of the late study for iodine-123 decomposition and determination of the parameters: heart / mediastinum ratio, radiopharmaceutical from the myocardium, an evaluation of the nature of the distribution radiopharmaceutical in relation to the region of maximum accumulation.
Visualization of the adrenal glands and the entire body is performed 24 hours after intravenous administration of the drug. After standard image processing, the presence of foci of hyperfixation radiopharmaceutical and bone marrow imaging. The level of accumulation in the outbreak is estimated by a standard method by comparing symmetrical areas: the adrenal region with the level of accumulation in the liver (the normal accumulation limit is 120-125%).
Normally, the whole body is visualized as a shadow. Increased accumulation radiopharmaceutical observed in salivary glands, in the heart, in the liver, in the bladder; weak accumulation in the intestine; the skeleton is not visualized. The visualization of the thyroid gland is carried out 10 minutes after the administration radiopharmaceutical on a gamma camera in the patient's position lying on his back by the standard method.